Li Dan, Xiao Zhitao, Wang Gang, Zhao Guoqing
The First Teaching Hospital, Jilin University, Changchun, Jilin 130021, P.R. China.
Department of Engineering Mechanics, Jilin University, Changchun, Jilin 130022, P.R. China.
Exp Ther Med. 2014 Jun;7(6):1583-1590. doi: 10.3892/etm.2014.1645. Epub 2014 Mar 28.
Constructing models based on computed tomography images for finite element analysis (FEA) is challenging under pathological conditions. In the present study, an innovative method was introduced that uses Siemens syngo 3D software for processing models and Mimics software for further modeling. Compared with the slice-by-slice traditional manual margin discrimination, the new 3D modeling method utilizes automatic tissue margin determination and 3D cutting using syngo software. The modeling morphologies of the two methods were similar; however, the 3D modeling method was 8-10 times faster than the traditional method, particularly in cases with osteoporosis and osteophytes. A comparative FEA study of the lumbar spines of young and elderly patients, on the basis of the models constructed by the 3D modeling method, showed peak stress elevation in the vertebrae of elderly patients. Stress distribution was homogeneous in the entire vertebrae of young individuals. By contrast, stress redistribution in the vertebrae of the elderly was concentrated in the anterior cortex of the vertebrae, which explains the high fracture risk mechanism in elderly individuals. In summary, the new 3D modeling method is highly efficient, accurate and faster than traditional methods. The method also allows reliable FEA in pathological cases with osteoporosis and osteophytes.
在病理条件下，基于计算机断层扫描图像构建有限元分析（FEA）模型具有挑战性。在本研究中，引入了一种创新方法，该方法使用西门子syngo 3D软件处理模型，并使用Mimics软件进行进一步建模。与逐片传统手动边缘判别相比，新的3D建模方法利用syngo软件进行自动组织边缘确定和3D切割。两种方法的建模形态相似；然而，3D建模方法比传统方法快8至10倍，尤其是在存在骨质疏松和骨赘的情况下。基于3D建模方法构建的模型，对年轻和老年患者腰椎进行的有限元分析比较研究表明，老年患者椎体的峰值应力升高。年轻个体整个椎体的应力分布均匀。相比之下，老年人椎体的应力重新分布集中在椎体的前皮质，这解释了老年人骨折风险高的机制。总之，新的3D建模方法高效、准确且比传统方法更快。该方法还允许在存在骨质疏松和骨赘的病理病例中进行可靠的有限元分析。
