Antitumor-promoting activity of eperisone.
作者信息
Takayasu J, Yamaoka Y, Nakagawa Y, Nishino H, Iwashima A
机构信息
Department of Biochemistry, Kyoto Prefectural University of Medicine, Japan.
出版信息
Oncology. 1989;46(1):58-60. doi: 10.1159/000226682.
PMID:2492653
Abstract
Eperisone, a Ca2+ entry blocker, suppressed the action of tumor promoter in vitro and in vivo, inhibited tumor-promoter-stimulated 32Pi incorporation into phospholipids of cultured cells, and also proved to have antitumor-promoting activity in mouse skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene plus tumor promoter, 12-O-tetradecanoylphorbol-13-acetate.
摘要
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