Prague Psychiatric Center and 3rd Medical School of Charles University, Prague, Czech Republic.
Int J Psychiatry Clin Pract. 2006;10(1):38-44. doi: 10.1080/13651500500305424.
Objectives. Relapse prevention is one of the most important goals of long-term schizophrenia management, as relapse is both distressing and costly. Family intervention supplementation to standard treatment could reduce the relapse rate. This study assessed the influence of a short-term, clinically based, and profesionally led family psychoeducation programme on a 1-year relapse rate. Methods. A total of 120 patients were recruited upon discharge from two psychiatric hospitals in Prague: (1) Site A (N=86), where family psychoeducation is offered to all patients with schizophrenia, schizoaffective disorder, and acute psychotic episode with schizophrenic symptoms; and (2) Site B (N=34), where no such programme was offered. Results. Compared to nonparticipants, psychoeducation participants had a shorter average length of rehospitalization stay (5.89 vs. 17.78 days, P=0.045) in a 1-year follow-up after discharge. The probability of rehospitalization during a 1-year follow-up was higher for patients from the site that did not provide psychoeducation. Conclusions. A shorter average length of rehospitalization of psychoeducation participants, a high turnout of first-episode patients, and positive responses of psychoeducation participants suggest that family psychoeducation should be supplemented early in the course of the illness to achieve favourable treatment outcomes and minimize adverse health and the social consequences of schizophrenia.
目的。预防复发是长期精神分裂症管理的最重要目标之一,因为复发不仅令人痛苦,而且代价高昂。家庭干预补充标准治疗可以降低复发率。本研究评估了短期、基于临床和专业主导的家庭心理教育方案对 1 年复发率的影响。
方法。总共招募了 120 名患者,他们在布拉格的两家精神病院出院后参加了研究:(1)A 地点(N=86),为所有精神分裂症、分裂情感障碍和伴有精神分裂症症状的急性精神病发作的患者提供家庭心理教育;(2)B 地点(N=34),未提供此类方案。
结果。与非参与者相比,在出院后 1 年的随访中,接受心理教育的参与者的平均再住院时间更短(5.89 天 vs. 17.78 天,P=0.045)。未提供心理教育的地点的患者在 1 年随访期间再住院的概率更高。
结论。心理教育参与者的平均再住院时间较短、首发患者的高参与率以及心理教育参与者的积极反应表明,应在疾病早期补充家庭心理教育,以实现良好的治疗效果,并最大程度地减少精神分裂症对健康和社会的不利影响。