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实性蓝点肿瘤:小唾液腺腺泡细胞癌。

Solid blue dot tumour: minor salivary gland acinic cell carcinoma.

作者信息

Bavle Radhika M, Makarla Soumya, Nadaf Afreen, Narasimhamurthy Srinath

机构信息

Department of Oral Pathology, Krishnadevaraya College of Dental Sciences, Bangalore, Karnataka, India.

Department of Oral Pathology, Government Dental College & Hospital, Srinagar, Jammu & Kashmir, India.

出版信息

BMJ Case Rep. 2014 Jun 13;2014:bcr2013200885. doi: 10.1136/bcr-2013-200885.

DOI:10.1136/bcr-2013-200885
PMID:24928927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4069807/
Abstract

Acinic cell adenocarcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of all primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and ACC is usually more frequent in women than men. Previous radiation exposure and familial predisposition are some of the risk factors for ACC. ACCs rarely involve minor salivary glands constituting only 13-17% of all minor salivary gland tumours. Generally, a slowly enlarging mass lesion in the tail of the parotid gland is the most frequent presentation. ACC has a significant tendency to recur, metastasise and may have an aggressive evolution. Therefore, a long-term follow-up is mandatory after treatment. Here we report the case of a woman in her 60s with an ACC in association with the labial minor salivary gland, presenting in the post-treatment period of squamous cell carcinoma of the tongue.

摘要

腺泡细胞腺癌(ACC)是一种低度恶性的涎腺肿瘤,约占所有原发性涎腺恶性肿瘤的17%。在头颈部区域,腮腺是主要的起源部位,ACC在女性中通常比男性更常见。既往放疗暴露和家族易感性是ACC的一些危险因素。ACC很少累及小涎腺,仅占所有小涎腺肿瘤的13-17%。一般来说,腮腺尾部缓慢增大的肿块病变是最常见的表现。ACC有显著的复发、转移倾向,可能会有侵袭性进展。因此,治疗后必须进行长期随访。在此,我们报告一例60多岁女性,其唇部小涎腺发生ACC,该病例出现在舌鳞状细胞癌的治疗后期。

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本文引用的文献

1
Acinic cell carcinoma of minor salivary gland of the base of tongue that required reconstructive surgery.舌根小唾液腺腺泡细胞癌,需行重建手术。
Case Rep Otolaryngol. 2012;2012:421065. doi: 10.1155/2012/421065. Epub 2012 Dec 12.
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Acinic cell carcinoma of the salivary glands: a retrospective clinicopathologic study of 12 cases.涎腺腺泡细胞癌:12例回顾性临床病理研究
Rom J Morphol Embryol. 2012;53(2):313-20.
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Radiotherapy in parotid acinic cell carcinoma: does it have an impact on survival?腮腺腺泡细胞癌的放射治疗:对生存率有影响吗?
Arch Otolaryngol Head Neck Surg. 2012 May;138(5):463-6. doi: 10.1001/archoto.2012.226.
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Salivary gland acinic cell carcinoma.唾液腺腺泡细胞癌
Ear Nose Throat J. 2010 Nov;89(11):530-2. doi: 10.1177/014556131008901109.
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Acinic cell carcinoma of minor salivary glands: a clinical and immunohistochemical study.小唾液腺腺泡细胞癌:一项临床与免疫组织化学研究。
J Oral Maxillofac Surg. 2010 Oct;68(10):2489-96. doi: 10.1016/j.joms.2009.09.065. Epub 2010 Aug 1.
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Acinic cell carcinoma of the salivary glands: a literature review.唾液腺腺泡细胞癌:文献综述
Hematol Oncol Stem Cell Ther. 2009;2(1):259-64. doi: 10.1016/s1658-3876(09)50035-0.
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Salivary gland tumours as second neoplasms: two cases and literature review.
J Laryngol Otol. 2010 May;124(5):577-80. doi: 10.1017/S0022215109991526. Epub 2009 Nov 19.
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Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review.我们能否降低放疗后发生第二原发性恶性肿瘤的发生率?一项批判性综述。
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Intra-oral minor salivary gland tumors: a clinicopathological study of 546 cases.口腔内小唾液腺肿瘤:546例临床病理研究
Oral Oncol. 2007 May;43(5):463-70. doi: 10.1016/j.oraloncology.2006.04.008. Epub 2006 Sep 18.
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Acinic cell carcinoma of the parotid gland in a child.儿童腮腺腺泡细胞癌。
Pediatr Surg Int. 2005 May;21(5):377-80. doi: 10.1007/s00383-005-1398-5. Epub 2005 Apr 2.