Aljishi Manaf, Parekh Ketna
RMO Unit, Wellington Hospital, Private Bag 7902, Wellington South, New Zealand.
N Z Med J. 2014 May 23;127(1394):42-50.
To investigate general medicine readmissions for risk factors and association with mortality.
A case control study was performed comparing the characteristics of 30-day general medicine patients readmitted between 1 January to 30 June 2012 to a general medicine service at Capital and Coast District Health Board (Wellington region, New Zealand) with an equal number of randomly selected patients not readmitted to the service during the same time period.
197 patients discharged from general medicine were readmitted during the 6-month study period. There were no differences in the sex, ethnicity, residential care at admission, history of dementia, length of admission or weekend discharge of readmitted patients compared to non-readmitted patients. The mean age, number of medications and comorbidities score were higher in the readmission group. Readmission (even after controlling for age, polypharmacy, and comorbidities) was a strong predictor of 1-year all-cause mortality, with an odds ratio of 2.2. Twenty-one percent of readmission patients had more than one general medicine readmission, up to 30 days between each, with even higher mortality rate compared to one readmission (49% vs. 28%).
Readmission to general medicine is strongly associated with older age, polypharmacy, and multiple comorbidities. Readmission is an independent strong risk factor for 1-year mortality, with this risk increasing after multiple readmissions. Readmissions can be a marker of deteriorating patient's condition, and a discussion in relation to prognosis, ceiling of treatment, resuscitation status documentation and advance directive may be warranted.
调查普通内科再入院的危险因素及其与死亡率的关联。
进行了一项病例对照研究,比较了2012年1月1日至6月30日期间因普通内科疾病再次入院至首都与海岸地区卫生局(新西兰惠灵顿地区)普通内科服务的30天患者的特征,与同期随机选择的未再次入院至该服务的同等数量患者的特征。
在为期6个月的研究期间,197名普通内科出院患者再次入院。与未再次入院的患者相比,再次入院患者在性别、种族、入院时的住院护理、痴呆病史、住院时间或周末出院方面没有差异。再次入院组的平均年龄、用药数量和合并症评分更高。再次入院(即使在控制了年龄、多种药物治疗和合并症之后)是1年全因死亡率的有力预测因素,优势比为2.2。21%的再次入院患者有不止一次普通内科再入院,每次再入院间隔最长30天,与单次再入院相比,死亡率更高(49%对28%)。
普通内科再入院与老年、多种药物治疗和多种合并症密切相关。再入院是1年死亡率的独立强危险因素,多次再入院后这种风险会增加。再入院可能是患者病情恶化的一个标志,可能有必要就预后、治疗上限、复苏状态记录和预先指示进行讨论。