Pfrimer Karina, Micheletto Rutinéia Fátima, Marchini Julio Sergio, Padovan Gilberto João, Moriguti Julio Cesar, Ferriolli Eduardo
Division of General Internal and Geriatric Medicine, School of Medicine of Ribeirão Preto, University of São Paulo, Brazil. ; Division of Clinical Nutrition, School of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Division of Clinical Nutrition, School of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Nutr Metab Insights. 2014 May 26;7:47-50. doi: 10.4137/NMI.S12977. eCollection 2014.
Data about the influence of aging on urinary excretion of iron and zinc are scarce. The objective of the present study was to compare the concentration of zinc and iron in the urine of healthy elderly subjects and younger adults.
Seven healthy elderly subjects and seven younger adults were selected and submitted to biochemical, clinical, and nutritional tests. After a fasting period, 12-hour urine was collected for the determination of iron and zinc concentrations by graphite furnace atomic absorption spectrophotometry.
Urinary zinc and iron concentrations of the elderly subjects were not significantly different from that of younger adults. However, the total zinc and iron urinary clearance in 24 hours for the elderly was significantly higher compared with that of younger adults.
There is an increase in urinary iron and zinc clearance with aging. The values reported in this manuscript may be used as references in future studies.
关于衰老对铁和锌尿排泄影响的数据很少。本研究的目的是比较健康老年受试者和年轻成年人尿液中锌和铁的浓度。
选取7名健康老年受试者和7名年轻成年人，进行生化、临床和营养测试。禁食一段时间后，收集12小时尿液，通过石墨炉原子吸收分光光度法测定铁和锌的浓度。
老年受试者的尿锌和铁浓度与年轻成年人无显著差异。然而，老年人24小时的总锌和铁尿清除率明显高于年轻成年人。
随着年龄增长，尿铁和锌清除率增加。本手稿中报告的值可作为未来研究的参考。
