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铒钇铝石榴石激光与酪蛋白磷酸肽-无定形磷酸钙联合对牙釉质脱矿抑制作用的体外研究

Combined effects of Er: YAG laser and casein phosphopeptide-amorphous calcium phosphate on the inhibition of enamel demineralization: An in vitro study.

作者信息

Yassaei Sogra, Shahraki Neda, Aghili Hossein, Davari Abdolrahim

机构信息

Department of Orthodontics, Faculty of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Department of Operative, Faculty of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Dent Res J (Isfahan). 2014 Mar;11(2):193-8.

PMID:24932189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4052644/
Abstract

BACKGROUND

Development of white spot lesions on enamel is a significant and common problem during the fixed orthodontic treatment. Various preventive methods have been suggested. The purpose of this study was to evaluate the preventive potential of MI Paste Plus, Er: YAG Laser and combined under similar in vitro conditions against demineralization.

MATERIALS AND METHODS

In this experimental in vitro study, 60 extracted premolars were randomly allocated to four groups (n = 15) of control, MI Paste Plus, Laser and MI + Laser (MIL). Enamel surface of each group was treated with one of above materials before and during the pH cycling for 12 days through a daily procedure of demineralization and remineralization for 3 h and 20 h, respectively. Teeth were sectioned and evaluated quantitatively by cross-sectional microhardness testing at 20 μm intervals from the outer enamel surface toward dentinoenamel junction up to 160 μm and data were analyzed using the one-way analysis of variance and Tukey test. P < 0.05 was considered as significant.

RESULTS

MIL group had the least amount of demineralization (P < 0.001). Control group (C group) had the greatest relative mineral loss and the laser group (L group) had 45% less mineral loss than the C group and there was no significant difference between the MI Paste Plus and L group (P = 0.154).

CONCLUSION

BASED ON THESE RESULTS, ER: YAG laser was able to decrease demineralization and was a potential alternative to preventive dentistry and was more effective when combined with casein phosphopeptide-amorphous calcium phosphate products.

摘要

背景

在固定正畸治疗期间,牙釉质上白斑病变的形成是一个重大且常见的问题。已提出了各种预防方法。本研究的目的是在相似的体外条件下评估MI Paste Plus、铒钇铝石榴石激光(Er:YAG Laser)以及两者联合使用对脱矿的预防潜力。

材料与方法

在这项体外实验研究中,60颗拔除的前磨牙被随机分为四组(n = 15),即对照组、MI Paste Plus组、激光组和MI + 激光组(MIL组)。在进行为期12天的pH循环之前和期间,通过每天分别进行3小时脱矿和20小时再矿化的程序,对每组的牙釉质表面用上述材料之一进行处理。将牙齿切片,并通过从牙釉质外表面向牙本质釉质界以20μm间隔直至160μm进行横断面显微硬度测试进行定量评估,使用单因素方差分析和Tukey检验对数据进行分析。P < 0.05被认为具有统计学意义。

结果

MIL组的脱矿量最少(P < 0.001)。对照组(C组)的相对矿物质损失最大,激光组(L组)的矿物质损失比C组少45%,并且MI Paste Plus组和L组之间没有显著差异(P = 0.154)。

结论

基于这些结果,铒钇铝石榴石激光能够减少脱矿,是预防牙科的一种潜在替代方法,并且与酪蛋白磷酸肽 - 无定形磷酸钙产品联合使用时更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10e3/4052644/aa1493743311/DRJ-11-193-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10e3/4052644/aa1493743311/DRJ-11-193-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10e3/4052644/aa1493743311/DRJ-11-193-g003.jpg

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本文引用的文献

1
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Angle Orthod. 2010 Sep;80(5):933-8. doi: 10.2319/110509-624.1.
2
Combining casein phosphopeptide-amorphous calcium phosphate with fluoride: synergistic remineralization potential of artificially demineralized enamel or not?酪蛋白磷酸肽-无定形磷酸钙与氟化物结合:人工脱矿釉质是否具有协同再矿化潜力?
J Biomed Opt. 2009 Jul-Aug;14(4):044039. doi: 10.1117/1.3210780.
3
The inhibitory effect of MI paste, fluoride and a combination of both on the progression of artificial caries-like lesions in enamel.
Effect of Er:YAG Laser Irradiation and Acidulated Phosphate Fluoride Therapy on Re-Mineralization of White Spot Lesions.
铒激光照射及含氟磷酸凝胶治疗对白斑再矿化的影响
J Dent (Shiraz). 2021 Sep;22(3):153-161. doi: 10.30476/DENTJODS.2020.86300.1187.
4
Rehardening of Eroded Enamel with CPP-ACFP Paste and CO Laser Treatment.CPP-ACFP 糊剂和 CO2 激光再矿化处理对酸蚀牙釉质的再硬化作用。
Biomed Res Int. 2021 Jul 14;2021:3304553. doi: 10.1155/2021/3304553. eCollection 2021.
5
The Effect of the Er:YAG Laser and MI Paste Plus on the Treatment of White Spot Lesions.铒钇铝石榴石激光与含氟化物的再矿化糊剂联合应用对白斑病变的治疗效果
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6
The effect of different re-mineralizing agents and diode laser irradiation on the microhardness of primary molar enamel: An study.不同再矿化剂和二极管激光照射对乳磨牙牙釉质微硬度的影响:一项研究。
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7
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J Clin Diagn Res. 2016 Dec;10(12):ZC10-ZC13. doi: 10.7860/JCDR/2016/21058.9007. Epub 2016 Dec 1.
MI糊剂、氟化物及其两者组合对釉质人工龋样病变进展的抑制作用。
Oper Dent. 2008 Sep-Oct;33(5):550-5. doi: 10.2341/07-136.
4
Calcium phosphate-based remineralization systems: scientific evidence?基于磷酸钙的再矿化系统:科学依据?
Aust Dent J. 2008 Sep;53(3):268-73. doi: 10.1111/j.1834-7819.2008.00061.x.
5
Fluoride and casein phosphopeptide-amorphous calcium phosphate.氟化物与酪蛋白磷酸肽-无定形磷酸钙
J Dent Res. 2008 Apr;87(4):344-8. doi: 10.1177/154405910808700420.
6
Fluoride uptake and acid resistance of enamel irradiated with Er:YAG laser.铒钇铝石榴石激光照射后牙釉质的氟摄取及抗酸性
Lasers Med Sci. 2008 Apr;23(2):141-7. doi: 10.1007/s10103-007-0466-6. Epub 2007 Sep 26.
7
Enamel Demineralization during Fixed Orthodontic Treatment - Incidence and Correlation to Various Oral-hygiene Parameters.固定正畸治疗期间的牙釉质脱矿——发病率及其与各种口腔卫生参数的相关性
J Orofac Orthop. 2007 Sep;68(5):353-63. doi: 10.1007/s00056-007-0714-1.
8
Prevention of white spot lesions in orthodontic practice: a contemporary review.正畸治疗中白斑病变的预防:当代综述
Aust Dent J. 2006 Dec;51(4):284-9; quiz 347. doi: 10.1111/j.1834-7819.2006.tb00445.x.
9
Increased remineralization of tooth enamel by milk containing added casein phosphopeptide-amorphous calcium phosphate.添加了酪蛋白磷酸肽-无定形磷酸钙的牛奶对牙釉质再矿化作用的增强。
J Dairy Res. 2006 Feb;73(1):74-8. doi: 10.1017/S0022029905001482.
10
Prevention of enamel demineralization: an in-vitro study using light-cured filled sealant.预防牙釉质脱矿:一项使用光固化填充封闭剂的体外研究。
Am J Orthod Dentofacial Orthop. 2005 Nov;128(5):592-600; quiz 670. doi: 10.1016/j.ajodo.2004.07.046.