Mohan Ravi Prakash Sasankoti, Gill Navneet, Verma Sankalp, Chawa Venkateshwar Rao, Tyagi Kuber, Agarwal Neha
Kothiwal Dental College and Research Centre, Moradabad, India.
College of Dental Sciences and Research Centre, Bopal, Ahmedabad, India.
Dent Res J (Isfahan). 2014 Mar;11(2):272-5.
The incidence of multiple myeloma (MM) affecting the jaws is 30% and on rare occasions the oral involvement can be the first indication of the disease. Authors report a case of MM in a 40-year-old woman who presented with a multilocular radiolucent lesion in the left mandible initially mistaken as an ameloblastoma. Conventional radiographs revealed a multilocular lesion on the molar region. Computed tomography (CT) and 3 dimensional CT revealed lytic, space occupying lesion perforating the inferior cortex. Magnetic resonance imaging (MRI) revealed a hypointense lesion on T1 weighted image and hyperintense lesion on T2 weighted image. Histopathological and lab investigations lead to the diagnosis of MM. MRI is superior in depicting the size of the lesion as compared to CT and conventional radiographs.
多发性骨髓瘤（MM）累及颌骨的发生率为30%，在极少数情况下，口腔受累可能是该疾病的首发表现。作者报告了一例40岁女性的MM病例，该患者最初左下颌出现多房性透射性病变，被误诊为成釉细胞瘤。传统X线片显示磨牙区有一多房性病变。计算机断层扫描（CT）和三维CT显示有溶骨性占位性病变，穿破下颌骨下缘皮质。磁共振成像（MRI）显示T1加权像上为低信号病变，T2加权像上为高信号病变。组织病理学和实验室检查确诊为MM。与CT和传统X线片相比，MRI在显示病变大小方面更具优势。
