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下颌骨病变作为一名年轻患者多发性骨髓瘤的首发症状。

Mandibular lesion as the first sign of multiple myeloma in a young patient.

作者信息

Pontes Flavia Sirotheau Correa, De Souza Lucas Lacerda, Fonseca Felipe Paiva, Pontes Helder Antônio Rebelo

机构信息

Department of Oral Pathology, João De Barros Barreto University Hospital, Federal University of Pará, Pará, Brazil.

Department of Oral Surgery and Pathology, Dental School, Federal University of Minas Gerais, Minas Gerais, Brazil.

出版信息

J Oral Maxillofac Pathol. 2019 Feb;23(Suppl 1):94-96. doi: 10.4103/jomfp.JOMFP_109_17.

DOI:10.4103/jomfp.JOMFP_109_17
PMID:30967735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6421928/
Abstract

Multiple myeloma (MM) is a malignant neoplasm characterized by an abnormal intramedullary plasma cell proliferation. It accounts for approximately 10% of all hematologic malignancies. It generally occurs between fourth and seventh decades of life, and it is predominant in male patients. Patients lower than 40 years are considered young, and only very few cases have been reported. We present a rare case of a 27-year-old man whose initial findings of MM were a swelling at the ramus of the mandible.

摘要

多发性骨髓瘤(MM)是一种恶性肿瘤,其特征为骨髓内浆细胞异常增殖。它约占所有血液系统恶性肿瘤的10%。通常发生在40至70岁之间,男性患者更为多见。40岁以下的患者被视为年轻患者,仅有极少数病例报道。我们报告一例罕见的27岁男性病例,其多发性骨髓瘤的最初表现为下颌支肿胀。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a7/6421928/33ded7fdefe4/JOMFP-23-94-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a7/6421928/4c3026642f97/JOMFP-23-94-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a7/6421928/33ded7fdefe4/JOMFP-23-94-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a7/6421928/4c3026642f97/JOMFP-23-94-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a7/6421928/33ded7fdefe4/JOMFP-23-94-g002.jpg

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本文引用的文献

1
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Case Rep Dent. 2015;2015:439536. doi: 10.1155/2015/439536. Epub 2015 Nov 12.
2
Multiple myeloma presenting with a maxillary lesion as the first sign.以颌骨病变为首发症状的多发性骨髓瘤。
Imaging Sci Dent. 2015 Mar;45(1):55-60. doi: 10.5624/isd.2015.45.1.55. Epub 2015 Mar 13.
3
Root resorption caused by jaw infiltration of multiple myeloma: report of a case and literature review.多发性骨髓瘤颌骨浸润引起的牙根吸收:一例报告及文献复习
J Endod. 2014 Aug;40(8):1260-4. doi: 10.1016/j.joen.2013.12.030. Epub 2014 Mar 6.
4
A multilocular radiolucency of mandible as the first evidence of multiple myeloma: A clinico-radiographic case report.下颌骨多房性透射区作为多发性骨髓瘤的首发证据:一例临床影像学病例报告
Dent Res J (Isfahan). 2014 Mar;11(2):272-5.
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Solitary plasmacytoma of the jaw.颌骨孤立性浆细胞瘤
J Craniofac Surg. 2011 Nov;22(6):e2-10. doi: 10.1097/SCS.0b013e31822ec79a.
6
Atypical imaging feature of non-secretory multiple myeloma.非分泌型多发性骨髓瘤的非典型影像学特征。
Ann Diagn Pathol. 2011 Aug;15(4):268-72. doi: 10.1016/j.anndiagpath.2011.01.010. Epub 2011 May 4.
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Multiple myeloma presenting as mandibular ill-defined radiolucent lesion with numb chin syndrome: a case report.以下颌骨边界不清的透射性病变伴颏部麻木综合征为表现的多发性骨髓瘤:一例报告
J Oral Maxillofac Surg. 2009 Sep;67(9):1991-6. doi: 10.1016/j.joms.2009.04.016.
8
Maxillary lesion presenting as a first sign of multiple myeloma: case report.上颌骨病变作为多发性骨髓瘤的首发症状:病例报告
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9
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10
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Dentomaxillofac Radiol. 2004 Nov;33(6):413-9. doi: 10.1259/dmfr/25951078.