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多导睡眠图与临床评估评分-15(CAS-15)用于治疗小儿睡眠呼吸障碍的成本效益分析。

Cost-benefit analysis of polysomnography versus Clinical Assessment Score-15 (CAS-15) for treatment of pediatric sleep-disordered breathing.

作者信息

Konka Anita, Weedon Jeremy, Goldstein Nira A

机构信息

Division of Pediatric Otolaryngology, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

Scientific Computing Center, State University of New York, Downstate Medical Center, Brooklyn, New York, USA.

出版信息

Otolaryngol Head Neck Surg. 2014 Sep;151(3):484-8. doi: 10.1177/0194599814536844. Epub 2014 Jun 16.

Abstract

OBJECTIVE

To determine the cost of medical care using the Clinical Assessment Score-15 (CAS-15) scale versus polysomnography (PSG) for children with sleep-disordered breathing in terms of benefit.

STUDY DESIGN

Cost-benefit analysis.

SETTING

Hospital-based pediatric otolaryngology practice.

SUBJECTS AND METHODS

Ninety-three patients from our original CAS-15 study were included. Four clinical measures were used and payment data were obtained. Cost-benefit analysis was performed for 2 clinical pathways. In pathway 1, all children had PSG; those with positive studies were referred for adenotonsillectomy. In pathway 2, children with CAS-15 ≥ 32 were referred for adenotonsillectomy regardless of PSG. Paired t test compared intrasubject mean total cost (pathway 1 vs pathway 2). Further analyses computed a change score for the clinical measures (follow-up minus baseline); these were divided by estimated treatment cost, producing 4 cost-benefit ratios for each pathway. Paired t tests compared the mean of these ratios between the pathways.

RESULTS

Of 65 PSG+ (15 CAS-), 54 underwent surgery; of 28 PSG- (17 CAS-), 7 underwent surgery. Model estimated costs demonstrate a mean cost benefit of $US1172 (SE = $214) for pathway 2 versus pathway 1 (P < .001). CAS-15 is also cost-beneficial versus PSG in 3 of 4 clinical measures (Child Behavior Checklist total problem T score, P = .008, mean OSA-18 survey score, P < .001, apnea hypopnea index, P < .001).

CONCLUSIONS

We present evidence that a CAS-15-based treatment decision criterion is superior to PSG in terms of monetary cost and in benefit per unit cost for 3 of 4 clinical measures evaluated.

摘要

目的

从效益方面确定使用临床评估评分 - 15(CAS - 15)量表与多导睡眠图(PSG)评估睡眠呼吸障碍儿童医疗护理的成本。

研究设计

成本效益分析。

研究地点

基于医院的儿科耳鼻喉科诊所。

研究对象与方法

纳入了我们原始CAS - 15研究中的93名患者。使用了四项临床指标并获取了支付数据。对两条临床路径进行了成本效益分析。在路径1中,所有儿童均进行PSG检查;检查结果为阳性的儿童被转诊至腺样体扁桃体切除术。在路径2中,CAS - 15≥32的儿童无论PSG检查结果如何均被转诊至腺样体扁桃体切除术。配对t检验比较了受试者内平均总成本(路径1与路径2)。进一步分析计算了临床指标的变化分数(随访值减去基线值);将这些变化分数除以估计的治疗成本,为每条路径得出4个成本效益比。配对t检验比较了两条路径之间这些比率的平均值。

结果

在65名PSG检查结果为阳性(15名CAS检查结果为阴性)的儿童中,54名接受了手术;在28名PSG检查结果为阴性(17名CAS检查结果为阴性)的儿童中,7名接受了手术。模型估计成本显示,路径2相对于路径1的平均成本效益为1172美元(标准误 = 214美元)(P < .001)。在四项临床指标中的三项(儿童行为检查表总问题T分数,P = .008;平均OSA - 18调查问卷分数,P < .001;呼吸暂停低通气指数,P < .001)中,CAS - 15相对于PSG也具有成本效益。

结论

我们提供的证据表明,基于CAS - 15的治疗决策标准在货币成本以及所评估的四项临床指标中的三项每单位成本效益方面均优于PSG。

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