Department of Bioengineering, Georgia Institute of Technology, Atlanta, United States.
Department of Biomedical Informatics, Emory University, Atlanta, United States.
Biomed Eng Online. 2022 Sep 12;21(1):66. doi: 10.1186/s12938-022-01033-3.
Obtaining medical data using wearable sensors is a potential replacement for in-hospital monitoring, but the lack of data for such sensors poses a challenge for development. One solution is using in-hospital recordings to boost performance via transfer learning. While there are many possible transfer learning algorithms, few have been tested in the domain of EEG-based sleep staging. Furthermore, there are few ways for determining which transfer learning method will work best besides exhaustive testing. Measures of transferability do exist, but are typically used for selection of pre-trained models rather than algorithms and few have been tested on medical signals. We tested several supervised transfer learning algorithms on a sleep staging task using a single channel of EEG (AF7-Fpz) captured from an in-home commercial system.
Two neural networks-one bespoke and another state-of-art open-source architecture-were pre-trained on one of six source datasets comprising 11,561 subjects undergoing clinical polysomnograms (PSGs), then re-trained on a target dataset of 75 full-night recordings from 24 subjects. Several transferability measures were then tested to determine which is most effective for assessing performance on unseen target data. Performance on the target dataset was improved using transfer learning, with re-training the head layers being the most effective in the majority of cases (up to 63.9% of cases). Transferability measures generally provided significant correlations with accuracy (up to [Formula: see text]).
Re-training the head layers provided the largest performance boost. Transferability measures are useful indicators of transfer learning effectiveness.
使用可穿戴传感器获取医疗数据是替代住院监测的一种潜在方法,但此类传感器缺乏数据,这对开发构成了挑战。一种解决方案是使用住院记录通过迁移学习来提高性能。虽然有许多可能的迁移学习算法,但在基于 EEG 的睡眠分期领域,很少有算法经过测试。此外,除了进行详尽的测试之外,很少有方法可以确定哪种迁移学习方法效果最佳。虽然存在可迁移性度量标准,但这些标准通常用于选择预训练模型,而不是算法,并且很少在医疗信号上进行测试。我们使用来自家庭式商业系统的单个 EEG 通道(AF7-Fpz)在睡眠分期任务上测试了几种监督式迁移学习算法。
我们在六个源数据集之一(包含 11561 名接受临床多导睡眠图(PSG)检查的患者)上对两个神经网络(一个是定制的,另一个是最先进的开源架构)进行了预训练,然后在 24 名患者的 75 个整夜记录的目标数据集上重新进行了训练。然后,我们使用了几种可迁移性度量标准来确定最适合评估未见目标数据性能的方法。使用迁移学习可以提高目标数据集的性能,在大多数情况下(多达 63.9%的情况下),重新训练头部层的效果最佳。可迁移性度量标准通常与准确性呈显著相关(高达[公式:请参见文本])。
重新训练头部层可提供最大的性能提升。可迁移性度量标准是迁移学习效果的有用指标。