Theman Todd A, Labow Brian I, Taghinia Amir
Department of Plastic and Oral Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA.
Department of Plastic and Oral Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA.
J Hand Surg Am. 2014 Aug;39(8):1585-90.e3. doi: 10.1016/j.jhsa.2014.04.041. Epub 2014 Jun 13.
Research abstracts presented during the proceedings of an annual meeting are often cited and can influence clinical practice. Prior studies show that roughly 50% of abstracts at American Society for Surgery of the Hand meetings are eventually published. Yet, it is unknown how often the results or conclusions of published studies differ from the podium presentation. The objective of this study was to quantify the differences between abstracts presented during the annual meeting of the American Society for Surgery of the Hand and the resulting manuscripts.
We retrospectively reviewed every abstract delivered as a podium presentation at the American Society for Surgery of the Hand annual meeting from 2000 to 2010. We searched the PubMed database for matching publications and compared authorship, country of origin, hypothesis, study design and methodology, changes in study groups or populations, results, and conclusions.
Of 798 total abstracts, we analyzed 719 involving the hand, wrist, and brachial plexus. Fifty-six different journals published 393 of the abstracts, for a 49% publication rate. Mean time to publication was 18 months with a median of 14 and maximum of 122 months. There were inconsistencies between the results and/or conclusions in 14% of full-length articles compared with the abstract presented at the meeting. A total of 9% of articles were published with fewer subjects. Authorships changes were noted in 54% of publications.
Abstracts represent preliminary investigations and major and minor changes occur before subsequent publication. Caution should be exercised in referencing abstracts or altering clinical practice based on their content.
TYPE OF STUDY/LEVEL OF EVIDENCE: Economic/decision analysis IV.
在年会过程中展示的研究摘要经常被引用，并可能影响临床实践。先前的研究表明，美国手外科协会会议上大约50%的摘要最终会被发表。然而，尚不清楚已发表研究的结果或结论与在讲台上展示的内容相比，出现差异的频率如何。本研究的目的是量化在美国手外科协会年会上展示的摘要与最终稿件之间的差异。
我们回顾性地审查了2000年至2010年在美国手外科协会年会上作为讲台展示的每一篇摘要。我们在PubMed数据库中搜索匹配的出版物，并比较了作者、原产国、假设、研究设计和方法、研究组或人群的变化、结果和结论。
在总共798篇摘要中，我们分析了719篇涉及手、腕和臂丛神经的摘要。56种不同的期刊发表了其中393篇摘要，发表率为49%。平均发表时间为18个月，中位数为14个月，最长为122个月。与会议上展示的摘要相比，14%的全文文章在结果和/或结论方面存在不一致。共有9%的文章发表时研究对象数量减少。54%的出版物中作者有所变动。
摘要代表初步研究，在后续发表之前会发生重大和微小的变化。在参考摘要或根据其内容改变临床实践时应谨慎。
研究类型/证据水平：经济/决策分析IV级。
