Servicio de Enfermedades del Sistema Inmune-Alergia, Hospital Universitario Príncipe de Asturias, Departamento de Medicina, Universidad de Alcalá, Carretera Alcalá-Meco S/N, 28805, Alcalá de Henares, Madrid, Spain,
Curr Allergy Asthma Rep. 2014 Jul;14(7):449. doi: 10.1007/s11882-014-0449-1.
Venom immunotherapy (VIT) is the most effective form of specific immunotherapy to date. Hitherto, several relevant queries remain unanswered, namely optimal doses, duration, and means of assessment. Important progress has been lately made in terms of diagnosis by means of component-resolved diagnosis. Moreover, basophil activation test results in patients with negative serum immunoglobulin E (IgE) and skin prick test confer this technique a promising future, although these outcomes shall be considered with caution. This review aims to unravel the important advances made on diagnosis, management, and prognosis and also focuses on several undetermined aspects of VIT.
毒液免疫疗法（VIT）是迄今为止最有效的特异性免疫疗法形式。迄今为止，仍有几个相关问题尚未得到解答，即最佳剂量、持续时间和评估方法。在通过成分解析诊断进行诊断方面最近取得了重要进展。此外，对于血清免疫球蛋白 E（IgE）和皮肤点刺试验均为阴性的患者，嗜碱性粒细胞激活试验结果为该技术提供了广阔的前景，尽管应谨慎考虑这些结果。本综述旨在阐明在诊断、管理和预后方面取得的重要进展，并重点介绍 VIT 的几个不确定方面。
