Dimai H P, Svedbom A, Fahrleitner-Pammer A, Resch H, Muschitz C, Thaler H, Szivak M, Amrein K, Borgström F
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Auenbruggerpl. 2, A-8036, Graz, Austria,
Osteoporos Int. 2014 Sep;25(9):2297-306. doi: 10.1007/s00198-014-2766-6. Epub 2014 Jun 17.
Only few studies have been published hitherto on country-specific incidence of distal forearm fracture. In the prevailing study, incidences were estimated, and trend analyses were performed for the entire Austrian population aged ≥50á. Incidence decreased significantly in women, but not in men, over the past 12 years of observation.
To estimate incidence of distal forearm fracture and assess incidence trends in the entire Austrian population aged ≥50á from 1989-2010 for inpatient fractures and from 1999 to 2010 for all fractures.
The number of inpatient forearm fractures was obtained from the Austrian Hospital Discharge Register (AHDR) for the entire population aged ≥50á from 1989 to 2010. Total number of distal forearm fractures was modeled using patient-level data on 36,327 patients with distal forearm fractures. Crude and age-standardized incidence rates (cases per 100,000) were estimated in 5-year age intervals. To analyze the change in incidence over time, average annual changes expressed as incidence rate ratios (IRR) were calculated.
For all distal forearm fractures, age-standardized incidence in women in 1999 and 2009 were estimated at 709 (95 % CI 675-743) and 607 (578-637), respectively. The age-standardized incidences in men the same years were estimated at 171 (156-185) and 162 (151-174), respectively. IRR analyses showed a significant decrease in women (-1.1 %, p < 0.01) but not in men (-0.8 %, p > 0.05) over the last 12 years (1999-2010).
Incidence of distal forearm fracture in the entire Austrian population is comparable to hip fracture incidence which is known to be among the highest worldwide. However, trend analyses reveal a significant decrease for all distal forearm fractures in women, but not in men, over the last 12 years.
迄今为止，关于特定国家前臂远端骨折发病率的研究仅有少数发表。在本研究中，对奥地利全体年龄≥50岁的人群的发病率进行了估算，并进行了趋势分析。在过去12年的观察期内，女性的发病率显著下降，而男性则没有。
估算奥地利全体年龄≥50岁人群中前臂远端骨折的发病率，并评估1989 - 2010年住院骨折以及1999年至2010年所有骨折的发病率趋势。
从奥地利医院出院登记册（AHDR）获取1989年至2010年全体年龄≥50岁人群的住院前臂骨折数量。使用36327例前臂远端骨折患者的个体水平数据对前臂远端骨折总数进行建模。按5岁年龄间隔估算粗发病率和年龄标准化发病率（每10万人中的病例数）。为分析发病率随时间的变化，计算了以发病率比（IRR）表示的年均变化。
对于所有前臂远端骨折，1999年和2009年女性的年龄标准化发病率分别估计为709（95%可信区间675 - 743）和607（578 - 637）。同年男性的年龄标准化发病率分别估计为171（156 - 185）和162（151 - 174）。IRR分析显示，在过去12年（1999 - 2010年）中，女性发病率显著下降（-1.1%，p < 0.01），而男性则没有（-0.8%，p > 0.05）。
奥地利全体人群中前臂远端骨折的发病率与已知在全球范围内处于最高水平的髋部骨折发病率相当。然而，趋势分析显示，在过去12年中，所有前臂远端骨折在女性中发病率显著下降，而男性则没有。
