Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Auenbruggerpl. 15, 8036, Graz, Austria.
Osteoporos Int. 2011 Feb;22(2):685-92. doi: 10.1007/s00198-010-1271-9. Epub 2010 May 11.
Hip fracture incidence rates in Austria over a period of 20 years (1989-2008) were assessed. Age-standardized incidence rates increased until 2005 but decreased thereafter. This change in the secular trend was primarily driven by a decrease in hip fracture incidence in women.
The aim of the prevailing study was to assess the incidence rates of hip fractures including changes in trend in the Austrian population over a period of 20 years (1989-2008).
The number of hip fractures was obtained from the Austrian Hospital Discharge Register for the entire population ≥ 50 years of age. A correction factor for multiple registrations of the same diagnosis was determined. Incidence rates (cases per 100,000) of hip fracture were calculated in 5-year age intervals. To analyze the overall change in hip fracture for the period, average annual change expressed as incidence rate ratios (IRRs) was calculated.
The age-standardized incidence in women increased until 2005, from 493 to 642, and decreased thereafter. In men, it increased at a measured pace until 2006, from 192 to 280, and decreased thereafter with a slight rebound in 2008. The age-standardized incidence in the entire population increased until 2005, from 376 to 496, and decreased thereafter. The IRR for the last 3 years (2006-2008) was significantly below the IRR for the first 17 years (0.94, ρ < 0.01), driven by a lower IRR in women (0.91, ρ < 0.01) and to a lesser extent by a lower IRR (not statistically significant) in men (0.96, ρ < 0.15).
The present study indicates that since 2006, age-standardized incidence of hip fractures has been declining in the Austrian population aged 50 years and above. This reversal in the secular trend has primarily been driven by a decrease in hip fracture incidence in women.
对奥地利 20 年来（1989-2008 年）髋部骨折发病率进行了评估。年龄标准化发病率在 2005 年前持续上升，但此后有所下降。这种长期趋势的变化主要是由于女性髋部骨折发病率的下降。
本研究旨在评估奥地利人群髋部骨折的发病率，包括 20 年来（1989-2008 年）的趋势变化。
从奥地利医院出院登记处获得了所有年龄≥50 岁人群的髋部骨折数量。确定了同一诊断多次登记的校正系数。以 5 年为间隔计算髋部骨折的发病率（每 10 万人中的病例数）。为分析该期间髋部骨折的总体变化，计算了平均年变化表示的发病率比（IRR）。
女性的年龄标准化发病率一直持续上升，直到 2005 年，从 493 增至 642，此后有所下降。男性的发病率以可衡量的速度持续上升，直到 2006 年，从 192 增至 280，此后略有下降，并在 2008 年出现轻微反弹。整个人群的年龄标准化发病率一直持续上升，直到 2005 年，从 376 增至 496，此后有所下降。最后 3 年（2006-2008 年）的 IRR 明显低于前 17 年（0.94，ρ<0.01），这主要是由于女性的 IRR 较低（0.91，ρ<0.01），男性的 IRR 略有下降（无统计学意义）（0.96，ρ<0.15）。
本研究表明，自 2006 年以来，奥地利 50 岁及以上人群的年龄标准化髋部骨折发病率一直在下降。这种长期趋势的逆转主要是由于女性髋部骨折发病率的下降。
