The MRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton SO16 6YD, UK.
Osteoporos Int. 2011 May;22(5):1277-88. doi: 10.1007/s00198-011-1601-6. Epub 2011 Apr 2.
Osteoporosis constitutes a major public health problem through its association with age-related fractures, most notably those of the proximal femur. Substantial geographic variation has been noted in the incidence of hip fracture throughout the world, and estimates of recent incidence trends have varied widely. Studies in the published literature have reported an increase, plateau, and decrease in age-adjusted incidence rates for hip fracture among both men and women. Accurate characterisation of these temporal trends is important in predicting the health care burden attributable to hip fracture in future decades. We therefore conducted a review of studies worldwide, addressing secular trends in the incidence of hip and other fractures. Studies in western populations, whether in North America, Europe or Oceania, have generally reported increases in hip fracture incidence through the second half of the last century, but those continuing to follow trends over the last two decades have found that rates stabilise with age-adjusted decreases being observed in certain centres. In contrast, some studies suggest that the rate is rising in Asia. This synthesis of temporal trends in the published literature will provide an important resource for preventing fractures. Understanding the reasons for the recent declines in rates of hip fracture may help understand ways to reduce rates of hip fracture worldwide.
骨质疏松症是一个主要的公共卫生问题,它与年龄相关的骨折有关,尤其是股骨近端骨折。在全球范围内,髋部骨折的发病率存在显著的地域差异,最近发病率趋势的估计也存在很大差异。已发表的文献中的研究报告表明,男性和女性的髋部骨折年龄调整发病率均呈上升、平稳和下降趋势。准确描述这些时间趋势对于预测未来几十年髋部骨折对医疗保健的负担非常重要。因此,我们对全球范围内的研究进行了综述,探讨了髋部和其他骨折发病率的变化趋势。在北美、欧洲和大洋洲等西方国家的研究中,髋部骨折的发病率通常在过去一个世纪的后半期呈上升趋势,但在过去二十年中继续跟踪趋势的研究发现,随着年龄调整的发病率下降,某些中心的发病率稳定下来。相比之下,一些研究表明亚洲的发病率在上升。本研究对文献中报道的时间趋势进行了综合分析,为预防骨折提供了重要资源。了解髋部骨折率近期下降的原因可能有助于了解全球范围内降低髋部骨折率的方法。