西澳大利亚户外休闲者感染斑点热群立克次体的血清流行病学研究。
Seroepidemiological study of outdoor recreationists' exposure to spotted fever group Rickettsia in Western Australia.
作者信息
Abdad Mohammad Y, Cook Angus, Dyer John, Stenos John, Fenwick Stanley G
机构信息
Australian Rickettsial Reference Laboratory, Geelong, Victoria, Australia; School of Population Health, University of Western Australia, Perth, Western Australia, Australia; Fremantle Hospital, Fremantle, Western Australia, Australia; School of Veterinary and Biomedical Science, Murdoch University, Murdoch, Western Australia, Australia
Australian Rickettsial Reference Laboratory, Geelong, Victoria, Australia; School of Population Health, University of Western Australia, Perth, Western Australia, Australia; Fremantle Hospital, Fremantle, Western Australia, Australia; School of Veterinary and Biomedical Science, Murdoch University, Murdoch, Western Australia, Australia.
出版信息
Am J Trop Med Hyg. 2014 Sep;91(3):584-8. doi: 10.4269/ajtmh.14-0102. Epub 2014 Jun 16.
Bushland activity has previously been linked to rickettsial exposure in eastern and central regions of Australia, whereas little is known about the risks in Western Australia. The isolation of Rickettsia gravesii sp. nov. from Amblyomma triguttatum ticks and anecdotal reports of low-grade illness among bush recreationists raised the possibility of rickettsial transmission in the State. This study investigated rickettsial seroprevalence and potential risk of exposure to the spotted fever group rickettsiae in rogainers. Our results showed that rogainers active in the bush had a significantly higher risk of seropositivity (immunofluorescence total antibody titer ≥ 128) for the spotted fever group Rickettsia (odds ratio [OR] = 14.02, 95% confidence interval [CI] = 1.38-142.07) compared with a reference population, the overall seroprevalence in the rogainer group being 23.1%.
在澳大利亚东部和中部地区，丛林活动此前一直与立克次氏体暴露有关，而西澳大利亚州的相关风险却鲜为人知。新种格雷夫斯立克次氏体（Rickettsia gravesii sp. nov.）从三盾花蜱（Amblyomma triguttatum）中分离出来，以及丛林活动者中出现的轻度疾病传闻，增加了该州存在立克次氏体传播的可能性。本研究调查了越野长跑参赛者中立克次氏体血清阳性率以及感染斑点热群立克次氏体的潜在风险。我们的结果显示，与参照人群相比，在丛林中活动的越野长跑参赛者感染斑点热群立克次氏体的血清阳性（免疫荧光总抗体滴度≥128）风险显著更高（优势比[OR]=14.02，95%置信区间[CI]=1.38 - 142.07），越野长跑参赛者群体的总体血清阳性率为23.1%。
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