• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

富含生长因子的血浆(PRGF)治疗精英运动员高位踝关节扭伤:一项随机对照试验。

Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial.

作者信息

Laver Lior, Carmont Michael R, McConkey Mark O, Palmanovich Ezequiel, Yaacobi Eyal, Mann Gideon, Nyska Meir, Kots Eugene, Mei-Dan Omer

机构信息

Department of Orthopaedic Surgery, Sports Medicine Unit, "Meir" Medical Center, The Sackler School of Medicine (Tel-Aviv University), Kfar-Saba, Israel.

Division of Sports Medicine, Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2015 Nov;23(11):3383-92. doi: 10.1007/s00167-014-3119-x. Epub 2014 Jun 18.

DOI:10.1007/s00167-014-3119-x
PMID:24938396
Abstract

PURPOSE

Syndesmotic sprains are uncommon injuries that require prolonged recovery. The influence of ultrasound-guided injections of platelet-rich plasma (PRP) into the injured antero-inferior tibio-fibular ligaments (AITFL) in athletes on return to play (RTP) and dynamic stability was studied.

METHODS

Sixteen elite athletes with AITFL tears were randomized to a treatment group receiving injections of PRP or to a control group. All patients followed an identical rehabilitation protocol and RTP criteria. Patients were prospectively evaluated for clinical ability to return to full activity and residual pain. Dynamic ultrasound examinations were performed at initial examination and at 6 weeks post-injury to demonstrate re-stabilization of the syndesmosis joint and correlation with subjective outcome.

RESULTS

All patients presented with a tear to the AITFL with dynamic syndesmosis instability in dorsiflexion-external rotation, and larger neutral tibia-fibula distance on ultrasound. Early diagnosis and treatment lead to shorter RTP, with 40.8 (±8.9) and 59.6 (±12.0) days for the PRP and control groups, respectively (p = 0.006). Significantly less residual pain upon return to activity was found in the PRP group; five patients (62.5 %) in the control group returned to play with minor discomfort versus one patient in the treatment group (12.5 %). One patient in the control group had continuous pain and disability and subsequently underwent syndesmosis reconstruction.

CONCLUSIONS

Athletes suffering from high ankle sprains benefit from ultrasound-guided PRP injections with a shorter RTP, re-stabilization of the syndesmosis joint and less long-term residual pain.

LEVEL OF EVIDENCE

II.

摘要

目的

下胫腓联合韧带扭伤是一种不常见的损伤,需要较长时间恢复。本研究探讨超声引导下向受伤的胫腓前下韧带(AITFL)注射富血小板血浆(PRP)对运动员重返赛场(RTP)和动态稳定性的影响。

方法

16名患有AITFL撕裂的精英运动员被随机分为接受PRP注射的治疗组和对照组。所有患者遵循相同的康复方案和RTP标准。对患者进行前瞻性评估,以确定其恢复完全活动的临床能力和残留疼痛情况。在初次检查时和受伤后6周进行动态超声检查,以显示下胫腓联合关节的重新稳定以及与主观结果的相关性。

结果

所有患者均表现为AITFL撕裂,在背屈-外旋时动态下胫腓联合不稳定,超声显示胫腓骨中立位间距增大。早期诊断和治疗导致RTP时间缩短,PRP组和对照组分别为40.8(±8.9)天和59.6(±12.0)天(p = 0.006)。PRP组在恢复活动时残留疼痛明显较少;对照组有5名患者(62.5%)在轻微不适的情况下重返赛场,而治疗组只有1名患者(12.5%)。对照组有1名患者持续疼痛且功能障碍,随后接受了下胫腓联合重建手术。

结论

患有高位踝关节扭伤的运动员受益于超声引导下的PRP注射,RTP时间缩短,下胫腓联合关节重新稳定且长期残留疼痛较少。

证据级别

II级。

相似文献

1
Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial.富含生长因子的血浆(PRGF)治疗精英运动员高位踝关节扭伤:一项随机对照试验。
Knee Surg Sports Traumatol Arthrosc. 2015 Nov;23(11):3383-92. doi: 10.1007/s00167-014-3119-x. Epub 2014 Jun 18.
2
Return to Play Following Ankle Sprain and Lateral Ligament Reconstruction.踝关节扭伤和外侧韧带重建后的重返运动
Clin Sports Med. 2016 Oct;35(4):697-709. doi: 10.1016/j.csm.2016.05.012. Epub 2016 Jun 22.
3
Stable Versus Unstable Grade II High Ankle Sprains: A Prospective Study Predicting the Need for Surgical Stabilization and Time to Return to Sports.稳定型与不稳定型Ⅱ度高位踝关节扭伤:一项预测手术稳定需求及恢复运动时间的前瞻性研究
Arthroscopy. 2016 Apr;32(4):634-42. doi: 10.1016/j.arthro.2015.10.003. Epub 2015 Dec 22.
4
Effect of aquatic versus conventional physical therapy program on ankle sprain grade III in elite athletes: randomized controlled trial.水上与常规物理治疗方案对精英运动员 III 级踝关节扭伤的效果:随机对照试验。
J Orthop Surg Res. 2024 Jul 11;19(1):400. doi: 10.1186/s13018-024-04855-0.
5
Anatomical reconstruction of the anterior inferior tibiofibular ligament in elite athletes using InternalBrace suture tape.使用 InternalBrace 缝线带对精英运动员的下胫腓前韧带进行解剖重建。
Bone Joint J. 2022 Jan;104-B(1):68-75. doi: 10.1302/0301-620X.104B1.BJJ-2021-0542.R2.
6
Suture Anchor Augmentation for Acute Unstable Isolated Ankle Syndesmosis Disruption in Athletes.运动员急性不稳定踝关节联合分离的缝线锚钉增强治疗。
Foot Ankle Int. 2021 Sep;42(9):1130-1137. doi: 10.1177/10711007211015188. Epub 2021 Jun 4.
7
Effectiveness of Mobilization of the Talus and Distal Fibula in the Management of Acute Lateral Ankle Sprain.距骨和腓骨远端松动在急性外踝扭伤治疗中的效果。
Phys Ther. 2021 Aug 1;101(8). doi: 10.1093/ptj/pzab111.
8
Editorial Commentary: Does Early Arthroscopy of Subtle Instability in High Ankle Sprains Hasten Return to Play in Elite Athletes?
Arthroscopy. 2016 Apr;32(4):643-4. doi: 10.1016/j.arthro.2016.01.015.
9
A dynamic ultrasound examination for the diagnosis of ankle syndesmotic injury in professional athletes: a preliminary study.动态超声检查在职业运动员踝关节下胫腓联合损伤诊断中的应用:一项初步研究
Am J Sports Med. 2009 May;37(5):1009-16. doi: 10.1177/0363546508331202. Epub 2009 Mar 31.
10
Noninvasive Interactive Neurostimulation Therapy for the Treatment of Low-Grade Lateral Ankle Sprain in the Professional Contact Sport Athlete Improves the Short-Term Recovery and Return to Sport: A Randomized Controlled Trial.无创交互式神经刺激疗法治疗职业接触性运动运动员低度外侧踝关节扭伤可改善短期恢复并促进重返运动:一项随机对照试验
J Foot Ankle Surg. 2019 May;58(3):441-446. doi: 10.1053/j.jfas.2018.09.009. Epub 2019 Mar 23.

引用本文的文献

1
Demographic, anthropometric and intrasubject variations affect platelet-rich plasma formulation.人口统计学、人体测量学和个体内差异会影响富血小板血浆制剂。
J Exp Orthop. 2025 Jan 26;12(1):e70024. doi: 10.1002/jeo2.70024. eCollection 2025 Jan.
2
Injection therapy in professional footballers.职业足球运动员的注射治疗。
Int Orthop. 2024 Nov;48(11):2827-2834. doi: 10.1007/s00264-024-06301-6. Epub 2024 Sep 16.
3
Owner-reported treatments and outcomes of perceived injuries to the thoracic and pelvic limb of agility dogs.主人报告的敏捷犬胸肢和盆腔肢感知损伤的治疗方法及结果。

本文引用的文献

1
Ultrasound guided injections of platelets rich plasma for muscle injury in professional athletes. Comparative study.超声引导下向职业运动员肌肉损伤部位注射富血小板血浆的比较研究。
Med Ultrason. 2013 Jun;15(2):101-5. doi: 10.11152/mu.2013.2066.152.rb1vy2.
2
Standardization of the functional syndesmosis widening by dynamic U.S examination.通过动态超声检查对功能性下胫腓联合增宽进行标准化评估。
BMC Sports Sci Med Rehabil. 2013 May 2;5:9. doi: 10.1186/2052-1847-5-9.
3
Histological study of the influence of plasma rich in growth factors (PRGF) on the healing of divided Achilles tendons in sheep.
Front Vet Sci. 2024 Aug 22;11:1409199. doi: 10.3389/fvets.2024.1409199. eCollection 2024.
4
Progress in diagnosis and treatment of acute injury to the anterior talofibular ligament.距腓前韧带急性损伤的诊断与治疗进展
World J Clin Cases. 2023 May 26;11(15):3395-3407. doi: 10.12998/wjcc.v11.i15.3395.
5
Efficacy of Platelet-Rich Plasma for Chronic Lateral Ankle Instability After Modified Broström-Gould surgery: A Randomized, Single-Blinded, Prospective Controlled Trial.富血小板血浆对改良 Broström-Gould 手术后慢性外侧踝关节不稳的疗效:一项随机、单盲、前瞻性对照试验
Foot Ankle Orthop. 2023 Apr 26;8(2):24730114231168633. doi: 10.1177/24730114231168633. eCollection 2023 Apr.
6
Advances in the Clinical Application of Platelet-Rich Plasma in the Foot and Ankle: A Review.富血小板血浆在足踝部临床应用的进展:综述
J Clin Med. 2023 Jan 28;12(3):1002. doi: 10.3390/jcm12031002.
7
Update on the Use of Platelet-Rich Plasma Injections in the Management of Musculoskeletal Injuries: A Systematic Review of Studies From 2014 to 2021.富血小板血浆注射在肌肉骨骼损伤管理中的应用进展:对2014年至2021年研究的系统评价
Orthop J Sports Med. 2022 Dec 9;10(12):23259671221140888. doi: 10.1177/23259671221140888. eCollection 2022 Dec.
8
Return to Play After Isolated Syndesmotic Ligamentous Injury in Athletes: A Systematic Review and Meta-analysis.运动员单纯下胫腓韧带损伤后的重返赛场:一项系统评价和荟萃分析。
Foot Ankle Orthop. 2022 May 16;7(2):24730114221096482. doi: 10.1177/24730114221096482. eCollection 2022 Apr.
9
Feasibility of Growth Factor Agent Therapy in Repairing Motor Injury.生长因子制剂疗法修复运动损伤的可行性
Front Pharmacol. 2022 Jan 25;13:842775. doi: 10.3389/fphar.2022.842775. eCollection 2022.
10
Clinical Cohort Study in Canine Patients, to Determine the Average Platelet and White Blood Cell Number and Its Correlation with Patient's Age, Weight, Breed and Gender: 92 Cases (2019-2020).犬类患者临床队列研究,以确定平均血小板和白细胞数量及其与患者年龄、体重、品种和性别的相关性:92例病例(2019 - 2020年)
Vet Sci. 2021 Nov 3;8(11):262. doi: 10.3390/vetsci8110262.
组织学研究富血小板血浆(PRGF)对绵羊分割跟腱愈合的影响。
J Bone Joint Surg Am. 2013 Feb 6;95(3):246-55. doi: 10.2106/JBJS.K.01659.
4
Epidemiology of syndesmosis injuries in intercollegiate football: incidence and risk factors from National Collegiate Athletic Association injury surveillance system data from 2004-2005 to 2008-2009.大学生足球比赛中踝关节联合损伤的流行病学:2004-2005 至 2008-2009 年美国大学生体育协会损伤监测系统数据的发生率和危险因素。
Clin J Sport Med. 2013 Jul;23(4):278-82. doi: 10.1097/JSM.0b013e31827ee829.
5
Platelet-rich plasma as an effective treatment for proximal hamstring injuries.富含血小板血浆作为近端腘绳肌损伤的有效治疗方法。
Orthopedics. 2013 Jan;36(1):e64-70. doi: 10.3928/01477447-20121217-20.
6
The effects of plasma rich in growth factors (PRGF-Endoret) on healing of medial collateral ligament of the knee.富含生长因子的血浆(PRGF-Endoret)对膝关节内侧副韧带愈合的影响。
Knee Surg Sports Traumatol Arthrosc. 2013 Aug;21(8):1763-9. doi: 10.1007/s00167-012-2002-x. Epub 2012 Apr 13.
7
Autologous platelet-rich plasma: a revolution in soft tissue sports injury management?自体富血小板血浆:软组织运动损伤管理的革命?
Phys Sportsmed. 2010 Dec;38(4):127-35. doi: 10.3810/psm.2010.12.1835.
8
Early return to play following complete rupture of the medial collateral ligament of the elbow using preparation rich in growth factors: a case report.
J Shoulder Elbow Surg. 2010 Jul;19(5):e1-5. doi: 10.1016/j.jse.2009.12.004.
9
Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up.自体血小板浓缩物在外侧肱骨上髁炎中的双盲随机对照试验中的积极作用:富血小板血浆与皮质类固醇注射的 1 年随访。
Am J Sports Med. 2010 Feb;38(2):255-62. doi: 10.1177/0363546509355445.
10
Platelet-rich plasma: any substance into it?富血小板血浆:其中含有任何物质吗?
Br J Sports Med. 2010 Jul;44(9):618-9. doi: 10.1136/bjsm.2009.067108. Epub 2010 Feb 4.