Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SE-171 77, Sweden.
Br J Dermatol. 2014 Sep;171(3):609-14. doi: 10.1111/bjd.13194. Epub 2014 Aug 16.
BAMSE is a Swedish population-based birth cohort.
To estimate prevalence proportions and the incidence rate of hand eczema in Swedish adolescents, and to compare information given by adolescents and parents. Further aims were to study sex distribution, age at onset and extension of hand eczema.
At 16 years of age, 2927 adolescents were included in this study; both adolescent and parental questionnaires were used, as well as clinical examination.
The 1-year prevalence of hand eczema was 5·2% (n = 152) and 4·0% (n = 116) (P < 0·03), and lifetime prevalence was 9·7% (n = 284) and 7·0% (n = 206) (P < 0·01), respectively, when adolescents and parents reported. The incidence rate was 573/100 000 person-years according to the adolescent report. The level of agreement between adolescents and parents was fair for 1-year and lifetime prevalence (κ = 0·56 and κ = 0·49, respectively). According to the Hand Eczema Extent Score, 27·0% (n = 36) had moderate-to-severe hand eczema.
At the age of 16 years, the 1-year prevalence of hand eczema was substantial, with an incidence rate of the same magnitude as in adults. Female predominance was seen in adolescence. It is preferable that the occurrence of hand eczema is reported by adolescents themselves, as they are the ones most aware of their symptoms.
BAMSE 是一个瑞典基于人群的出生队列。
估计瑞典青少年手部湿疹的患病率和发病率，并比较青少年和父母提供的信息。进一步的目的是研究性别分布、发病年龄和手部湿疹的扩展。
在 16 岁时，纳入了 2927 名青少年；使用了青少年和父母的问卷以及临床检查。
1 年手部湿疹的患病率为 5.2%（n = 152）和 4.0%（n = 116）（P < 0.03），终生患病率为 9.7%（n = 284）和 7.0%（n = 206）（P < 0.01），分别由青少年和父母报告。根据青少年报告，发病率为 573/100000 人年。青少年和父母之间的 1 年和终生患病率的一致性程度为中度（κ = 0.56 和 κ = 0.49）。根据手部湿疹严重程度评分，27.0%（n = 36）有中重度手部湿疹。
在 16 岁时，手部湿疹的 1 年患病率相当高，发病率与成年人相同。在青春期，女性占优势。最好由青少年自己报告手部湿疹的发生，因为他们最了解自己的症状。
