Reprogramming the response to stroke by preconditioning.
作者信息
Stevens Susan L, Vartanian Keri B, Stenzel-Poore Mary P
机构信息
From the Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland.
出版信息
Stroke. 2014 Aug;45(8):2527-31. doi: 10.1161/STROKEAHA.114.002879. Epub 2014 Jun 17.
Abstract
摘要
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Stroke. 2014 Aug;45(8):2527-31. doi: 10.1161/STROKEAHA.114.002879. Epub 2014 Jun 17.
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Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy.Tsc1（错构瘤蛋白）通过诱导自噬发挥神经保护作用对抗缺血。
Nat Med. 2013 Mar;19(3):351-7. doi: 10.1038/nm.3097. Epub 2013 Feb 24.
2
Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy.研究观察：美国食品和药物管理局批准的用于癌症治疗的 Toll 样受体激动剂。
Oncoimmunology. 2012 Sep 1;1(6):894-907. doi: 10.4161/onci.20931.
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TLR9 bone marrow chimeric mice define a role for cerebral TNF in neuroprotection induced by CpG preconditioning.TLR9 骨髓嵌合小鼠确定了 CpG 预处理诱导的神经保护作用中大脑 TNF 的作用。
J Cereb Blood Flow Metab. 2012 Dec;32(12):2193-200. doi: 10.1038/jcbfm.2012.140. Epub 2012 Sep 26.
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Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism.Toll 样受体 7 预处理通过新型 I 型干扰素介导的机制诱导强烈的神经保护作用抵抗中风。
Stroke. 2012 May;43(5):1383-9. doi: 10.1161/STROKEAHA.111.641522. Epub 2012 Mar 8.
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Clinical applications of remote ischemic preconditioning.远程缺血预处理的临床应用。
Cardiol Res Pract. 2012;2012:620681. doi: 10.1155/2012/620681. Epub 2012 Feb 14.
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Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury.多种预处理方案集中于干扰素调节因子依赖性信号传导，以促进对缺血性脑损伤的耐受。
J Neurosci. 2011 Jun 8;31(23):8456-63. doi: 10.1523/JNEUROSCI.0821-11.2011.
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Proof of concept: pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke.概念验证： Toll 样受体激动剂的药理学预处理可预防灵长类中风模型中的脑血管损伤。
J Cereb Blood Flow Metab. 2011 May;31(5):1229-42. doi: 10.1038/jcbfm.2011.6. Epub 2011 Feb 2.
8
A broad upregulation of cerebral chemokine genes by peripherally-generated inflammatory mediators.外周炎症介质引起脑趋化因子基因的广泛上调。
Metab Brain Dis. 2011 Mar;26(1):49-59. doi: 10.1007/s11011-010-9231-9. Epub 2011 Jan 22.
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MicroRNAs induced during ischemic preconditioning.缺血预处理诱导的 microRNAs。
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Vasc Endovascular Surg. 2010 Aug;44(6):434-9. doi: 10.1177/1538574410369709. Epub 2010 May 18.
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