空腹血糖在妊娠期糖尿病筛查中的重要性。
The importance of fasting blood glucose in screening for gestational diabetes.
作者信息
Herrera Kimberly, Brustman Lois, Foroutan Janelle, Scarpelli Sophia, Murphy Elizabeth, Francis Antonia, Rosenn Barak
机构信息
Department of Obstetrics & Gynecology, St. Luke's-Roosevelt Hospital Center , New York , USA.
出版信息
J Matern Fetal Neonatal Med. 2015 May;28(7):825-8. doi: 10.3109/14767058.2014.935322. Epub 2014 Jul 11.
OBJECTIVE
To determine how well an isolated abnormal fasting blood glucose (FBG) value on the 1-step, 75-g, 2-hour glucose tolerance test (GTT) indicates significant gestational diabetes (GDM).
METHODS
Retrospective cohort study, January 2011 to May 2012. Patients diagnosed by the 1-step method were assigned by their abnormal results to the isolated fasting (FBG), isolated 1-hour (1HBG), isolated 2-hour (2HBG), or multiple-value (≥2BG) group. Characteristics and outcomes were compared using ANOVA, Kruskal--Wallis, and Chi-squared tests.
RESULTS
324 patients were included. Compared to other groups, the FBG group (N = 23) had the highest incidence of requiring medical therapy (78.26%), mean body mass index (29.40 ± 6.20 kg/m(2)), and percentage of Black plus Hispanic women (60.87%).
CONCLUSIONS
Seven percent of women were diagnosed with GDM by an isolated abnormal fasting BG and have significant disease. This group should not be missed; therefore, fasting BG should be integrated into all GDM screening.
目的
确定在一步法75克2小时葡萄糖耐量试验（GTT）中，孤立的空腹血糖（FBG）异常值对显著妊娠期糖尿病（GDM）的指示效果如何。
方法
回顾性队列研究，2011年1月至2012年5月。采用一步法诊断的患者根据其异常结果被分为孤立空腹（FBG）组、孤立1小时（1HBG）组、孤立2小时（2HBG）组或多值（≥2BG）组。使用方差分析、Kruskal-Wallis检验和卡方检验比较各组特征和结局。
结果
共纳入324例患者。与其他组相比，FBG组（N = 23）需要药物治疗的发生率最高（78.26%），平均体重指数最高（29.40±6.20kg/m²），黑人加西班牙裔女性的比例最高（60.87%）。
结论
7%的女性通过孤立的空腹血糖异常被诊断为GDM，且患有严重疾病。该组患者不应被漏诊；因此，空腹血糖应纳入所有GDM筛查。
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