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A critical analysis of testosterone supplementation therapy and cardiovascular risk in elderly men.

作者信息

Scovell Jason, Ramasamy Ranjith, Kovac Jason R

机构信息

Scott Department of Urology, Baylor College of Medicine, Houston, TX;

Urology of Indiana, Greenwood, IN.

出版信息

Can Urol Assoc J. 2014 May;8(5-6):E356-7. doi: 10.5489/cuaj.1962.

DOI:10.5489/cuaj.1962
PMID:24940464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4039601/
Abstract
摘要

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本文引用的文献

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Words of wisdom. Re: In older men an optimal plasma testosterone is associated with reduced all-cause mortality and higher dihydrotestosterone with reduced ischemic heart disease mortality, while estradiol levels do not predict mortality.至理名言。回复：在老年男性中，最佳血浆睾酮水平与全因死亡率降低相关，较高的双氢睾酮水平与缺血性心脏病死亡率降低相关，而雌二醇水平不能预测死亡率。
Eur Urol. 2014 Apr;65(4):844-5. doi: 10.1016/j.eururo.2013.12.030.
2
Risks of testosterone therapy in elderly men.老年男性睾酮治疗的风险。
F1000Res. 2014 Jan 15;3:11. doi: 10.12688/f1000research.3-11.v1. eCollection 2014.
3
Increased risk of non-fatal myocardial infarction following testosterone therapy prescription in men.男性使用睾酮治疗处方后非致命性心肌梗死风险增加。
PLoS One. 2014 Jan 29;9(1):e85805. doi: 10.1371/journal.pone.0085805. eCollection 2014.
4
Testosterone replacement therapy improves metabolic parameters in hypogonadal men with type 2 diabetes but not in men with coexisting depression: the BLAST study.睾酮替代疗法可改善 2 型糖尿病伴性腺功能减退症男性的代谢参数，但不能改善合并抑郁症男性的代谢参数：BLAST 研究。
J Sex Med. 2014 Mar;11(3):840-56. doi: 10.1111/jsm.12404. Epub 2013 Dec 6.
5
In older men an optimal plasma testosterone is associated with reduced all-cause mortality and higher dihydrotestosterone with reduced ischemic heart disease mortality, while estradiol levels do not predict mortality.在老年男性中，最佳的血浆睾酮水平与全因死亡率降低有关，而较高的二氢睾酮水平与缺血性心脏病死亡率降低有关，而雌二醇水平则与死亡率无关。
J Clin Endocrinol Metab. 2014 Jan;99(1):E9-18. doi: 10.1210/jc.2013-3272. Epub 2013 Dec 20.
6
Association of testosterone therapy with mortality, myocardial infarction, and stroke in men with low testosterone levels.睾酮治疗与低睾酮水平男性的死亡率、心肌梗死和中风的关联。
JAMA. 2013 Nov 6;310(17):1829-36. doi: 10.1001/jama.2013.280386.
7
Trends in androgen prescribing in the United States, 2001 to 2011.2001年至2011年美国雄激素处方趋势
JAMA Intern Med. 2013 Aug 12;173(15):1465-6. doi: 10.1001/jamainternmed.2013.6895.
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Effectiveness and safety of phosphodiesterase 5 inhibitors in patients with cardiovascular disease and hypertension.磷酸二酯酶 5 抑制剂在心血管疾病和高血压患者中的疗效和安全性。
Curr Hypertens Rep. 2013 Oct;15(5):475-83. doi: 10.1007/s11906-013-0377-9.
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Cardiometabolic risks during anabolic hormone supplementation in older men.老年男性在补充合成代谢激素期间的心脏代谢风险。
Obesity (Silver Spring). 2013 May;21(5):968-75. doi: 10.1002/oby.20081.
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Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials.睾酮治疗与男性心血管事件：安慰剂对照随机试验的系统评价和荟萃分析。
BMC Med. 2013 Apr 18;11:108. doi: 10.1186/1741-7015-11-108.