Fargher R C, McKeown B A
Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Gen Comp Endocrinol. 1989 Mar;73(3):398-403. doi: 10.1016/0016-6480(89)90197-4.
The response of plasma prolactin (PRL) to manipulations of plasma calcium were investigated in coho salmon. Injection of 3.16 mumol EGTA/10 g body weight (to reduce the plasma calcium activity) resulted in significantly higher plasma PRL levels. Lower doses of EGTA (1.06 and 2.13 mumol/10 g body wt) had no effect on plasma PRL concentrations. Injection of 8.75 mumol CaCl2/10 g body wt (but not 4.35 mumol CaCl2/10 g body wt) resulted in significantly lower plasma PRL levels. Plasma total calcium and sodium concentrations were significantly elevated following three daily injections of 0.5 micrograms/g pure chum salmon PRL. This is the first report of a role for salmon PRL in calcium homeostasis of Oncorhynchus.
