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[早期胃癌:流行病学、诊断与治疗]

[Early gastric cancer: epidemiology, diagnostic and management].

作者信息

Koessler T, Roth A, Cacheux W

出版信息

Rev Med Suisse. 2014 May 21;10(431):1118-22.

PMID:24941682
Abstract

Stomach cancers are diagnosed at an early stage in less than 10% of cases in Europe. They are superficial tumours, involving the mucosa and the submucosa only. Node involvement is the most important prognostic factor for these tumours. To determine the optimal therapeutic strategy, it is necessary to carry out a precise work-up involving an endoscopy, with chemical or virtual colorations and an echo-endoscopy. Gastric surgery is the reference treatment. Nowadays, endoscopic tumour resection is a validated curative alternative. High quality medical expertise is needed for those tumours with a good prognosis, after evaluating risk for node involvement, and should be followed by Helicobacter pylori eradication and regular endoscopic surveillance.

摘要

在欧洲,不到10%的胃癌病例在早期被诊断出来。它们是浅表肿瘤,仅累及黏膜和黏膜下层。淋巴结受累是这些肿瘤最重要的预后因素。为了确定最佳治疗策略,有必要进行精确的检查,包括内镜检查、化学或虚拟染色以及超声内镜检查。胃手术是参考治疗方法。如今,内镜肿瘤切除术是一种经过验证的根治性替代方法。对于预后良好的肿瘤,在评估淋巴结受累风险后,需要高质量的医学专业知识,随后应进行幽门螺杆菌根除和定期内镜监测。

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