Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
Gastroenterol Clin North Am. 2013 Jun;42(2):317-35. doi: 10.1016/j.gtc.2013.01.007. Epub 2013 Mar 27.
Early gastric cancer is defined as adenocarcinoma confined to the mucosa or submucosa irrespective of lymph node involvement. In Japan, mucosal high-grade neoplasia is diagnosed as intramucosal early gastric cancer. Some early gastric cancers progress to advanced gastric cancer after several years of follow-up. Image-enhanced endoscopy (chromoendoscopy), narrow-band imaging, and magnifying endoscopy increase the diagnostic yield in characterizing early gastric cancer. Endoscopic resection of intramucosal early gastric cancer with endoscopic mucosal resection or endoscopic submucosal dissection is currently performed in East Asian countries to prevent the development of advanced gastric cancer and preserve patients' quality of life after treatment.
早期胃癌是指腺癌局限于黏膜或黏膜下层，无论是否有淋巴结受累。在日本，黏膜高级别肿瘤被诊断为黏膜内早期胃癌。一些早期胃癌在随访数年后会进展为进展期胃癌。增强内镜（染色内镜）、窄带成像和放大内镜提高了早期胃癌特征诊断的检出率。在东亚国家，目前采用内镜黏膜切除术或内镜黏膜下剥离术对黏膜内早期胃癌进行内镜下切除，以预防进展期胃癌的发生，并在治疗后保留患者的生活质量。
