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使用5%利多卡因贴片治疗小儿患者1型复杂性区域疼痛综合征:一例报告。

Treatment of complex regional pain syndrome type 1 in a pediatric patient using the lidocaine patch 5%: a case report.

作者信息

Frost Steven G

机构信息

Regional Pain Management Center, Rapid City, South Dakota USA.

出版信息

Curr Ther Res Clin Exp. 2003 Sep;64(8):626-9. doi: 10.1016/j.curtheres.2003.09.010.

Abstract

BACKGROUND

Successful treatment of complex regional pain syndrome type 1 (CRPS-1) requires a coordinated, multidisciplinary approach. Physical rehabilitation is an important component of long-term treatment. Unfortunately, patients with significant allodynia or hyperalgesia characteristic of CRPS-1 often have difficulty progressing through a physical therapy (PT) regimen. In most adults with CRPS-1, the treatment of choice is PO opioids.

OBJECTIVE

This article presents a case report of the use of the lidocaine patch 5%, a targeted peripheral analgesic, in a pediatric patient and its effects on reducing pain, improving the patient's overall attitude, and facilitating compliance with ongoing PT.

RESULTS

A 10-year-old girl developed CRPS-1 after arthroscopic surgery for a sprained ankle. Attempts at PT were unsuccessful due to inadequate pain relief from various treatment modalities. Therapy with the lidocaine patch 5% was initiated and resulted in significant pain relief, improvements in the patient's attitude, and progress with PT.

CONCLUSION

This case report of a child with CRPS-1 showed that therapy with lidocaine patch 5% may be efficacious in treating children with pain resulting from CRPS-1, thereby increasing the success of PT.

摘要

背景

成功治疗1型复杂性区域疼痛综合征(CRPS-1)需要一种协调的多学科方法。物理康复是长期治疗的重要组成部分。不幸的是,具有CRPS-1典型的明显痛觉过敏或痛觉超敏的患者在进行物理治疗(PT)方案时往往进展困难。在大多数成年CRPS-1患者中,首选治疗方法是口服阿片类药物。

目的

本文介绍了一例在儿科患者中使用5%利多卡因贴剂(一种靶向外周镇痛药)的病例报告,以及其在减轻疼痛、改善患者总体态度和促进患者配合持续PT治疗方面的效果。

结果

一名10岁女孩在踝关节扭伤的关节镜手术后患上CRPS-1。由于各种治疗方式的疼痛缓解不足,PT尝试未成功。开始使用5%利多卡因贴剂治疗后,疼痛得到显著缓解,患者态度有所改善,PT治疗取得进展。

结论

这例CRPS-1患儿的病例报告表明,5%利多卡因贴剂治疗可能对治疗因CRPS-1导致疼痛的儿童有效,从而提高PT治疗的成功率。

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本文引用的文献

1
Topical lidocaine patch relieves a variety of neuropathic pain conditions: an open-label study.
Clin J Pain. 2000 Sep;16(3):205-8. doi: 10.1097/00002508-200009000-00005.
2
Complex Regional Pain Syndromes: guidelines for therapy.复杂性区域疼痛综合征:治疗指南
Clin J Pain. 1998 Jun;14(2):155-66. doi: 10.1097/00002508-199806000-00012.

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