Park Young-Seok, Kim Sungtae, Oh Seung-Hee, Park Hee-Jung, Lee Sophia, Kim Tae-Il, Lee Young-Kyu, Heo Min-Suk
Department of Oral Anatomy, Seoul National University School of Dentistry, Seoul, Korea.
Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
Imaging Sci Dent. 2014 Jun;44(2):143-8. doi: 10.5624/isd.2014.44.2.143. Epub 2014 Jun 11.
This study evaluated the efficacy of alveolar ridge preservation methods with and without primary wound closure and the relationship between histometric and micro-computed tomographic (CT) data.
Porcine hydroxyapatite with polytetrafluoroethylene membrane was implanted into a canine extraction socket. The density of the total mineralized tissue, remaining hydroxyapatite, and new bone was analyzed by histometry and micro-CT. The statistical association between these methods was evaluated.
Histometry and micro-CT showed that the group which underwent alveolar preservation without primary wound closure had significantly higher new bone density than the group with primary wound closure (P<0.05). However, there was no significant association between the data from histometry and micro-CT analysis.
These results suggest that alveolar ridge preservation without primary wound closure enhanced new bone formation more effectively than that with primary wound closure. Further investigation is needed with respect to the comparison of histometry and micro-CT analysis.
本研究评估了有无一期伤口闭合的牙槽嵴保存方法的疗效，以及组织计量学数据与微型计算机断层扫描（CT）数据之间的关系。
将含聚四氟乙烯膜的猪羟基磷灰石植入犬拔牙窝。通过组织计量学和微型CT分析总矿化组织、剩余羟基磷灰石和新骨的密度。评估了这些方法之间的统计学关联。
组织计量学和微型CT显示，未进行一期伤口闭合的牙槽嵴保存组的新骨密度显著高于进行一期伤口闭合的组（P<0.05）。然而，组织计量学数据与微型CT分析数据之间无显著关联。
这些结果表明，未进行一期伤口闭合时牙槽嵴保存比进行一期伤口闭合时能更有效地促进新骨形成。关于组织计量学与微型CT分析的比较还需要进一步研究。
