Hirsch D J
Department of Medicine, Dalhousie University, Halifax, Nova Scotia.
Nephrol Dial Transplant. 1989;4(1):41-4.
The only detailed analysis of dialysis termination by viable patients was reported by Neu and Kjellstrand (N Engl J Med 1986; 314: 14-20) from the USA. We analysed a similar series from Halifax, Nova Scotia, to add to our understanding of this important mode of treatment rejection by dialysis patients. Of 178 chronic dialysis patients at risk from January 1982 to May 1987, 11 viable patients (6%) stopped dialysis (16% of all patient deaths) after a mean of 22 +/- 7 months of therapy. Mean age at death was 67 +/- 5 years. The majority of these patients were receiving in-centre haemodialysis. Six patients independently decided to stop therapy, while in three cases physicians first proposed termination. In only two cases did the family propose termination. All patients died in hospital a mean of 10 +/- 2 days after the last dialysis. Dementia was the reason for stopping treatment in only two cases, while chronic heart failure with poor exercise tolerance was the major precipitant. One patient suffered from diabetes mellitus. We were not able to differentiate patients terminating therapy from those continuing treatment on the basis of age or co-morbidity, suggesting that subjective patient perception of their condition is a critical factor in stopping dialysis.
美国的Neu和Kjellstrand(《新英格兰医学杂志》1986年;314卷:14 - 20页)报道了对存活患者终止透析情况的唯一详细分析。我们分析了来自新斯科舍省哈利法克斯的类似病例系列,以增进我们对透析患者拒绝这种重要治疗方式的理解。在1982年1月至1987年5月期间有终止透析风险的178例慢性透析患者中,11例存活患者(6%)在平均接受22±7个月的治疗后停止了透析(占所有患者死亡的16%)。死亡时的平均年龄为67±5岁。这些患者大多数接受的是中心血液透析。6例患者自主决定停止治疗,3例是医生首先提出终止治疗。只有2例是家属提出终止治疗。所有患者在最后一次透析后平均10±2天在医院死亡。仅2例患者因痴呆停止治疗,而慢性心力衰竭伴运动耐量差是主要诱因。1例患者患有糖尿病。我们无法根据年龄或合并症将终止治疗的患者与继续治疗的患者区分开来,这表明患者对自身状况的主观认知是停止透析的关键因素。