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精神疾病患者的药物信息:一项随机对照试验。

Drug information for the mentally ill: A randomized controlled trial.

机构信息

Forston Clinic, Dorchester, UK.

出版信息

Int J Psychiatry Clin Pract. 1998;2(2):121-7. doi: 10.3109/13651509809115344.

DOI:10.3109/13651509809115344
PMID:24946292
Abstract

Drugs play a significant role in maintaining the health of the mentally ill Lack of information is known to be one of the chief reasons for patients' failure to adhere to prescribed regimens. This study was designed to evaluate the impact of drug information leaflets for mentally ill patients on knowledge and satisfaction concerning psychotropic drug therapy. We conducted a randomized controlled trial of 249 adult general psychiatry patients (124 inpatients and 125 community patients), half assigned to the invervention (i.e., patient information leaflets; these patients also received the usual information) (n = 120) and half receiving the usual information only (n = 129). The assessments were made using a semi-structured questionnaire. The mean total knowledge score was significantly higher with intervention in both acute and community patients. Analysis of individual aspects of knowledge showed a marked lack of knowledge in the areas of side-effects and precautions, which improved significantly with intervention. Patients in the community showed a greater awareness of their drug therapy than did inpatients. Improvement in knowledge was evident in all diagnostic groups. There was no significant relationship with age, sex, level of education and number of drugs. Overall, 60% of controls and 79% of leaflet patients were satisfied with their drug information. Patient information leaflets provided a useful source of reference for the patients and the carers.

摘要

药物在维护精神疾病患者的健康方面发挥着重要作用。信息缺乏是导致患者无法遵守规定治疗方案的主要原因之一。本研究旨在评估精神疾病患者药物信息传单对精神药物治疗知识和满意度的影响。我们对 249 名成年综合精神病患者(124 名住院患者和 125 名社区患者)进行了随机对照试验,其中一半患者被分配到干预组(即患者信息传单;这些患者还接受了常规信息)(n = 120),另一半仅接受常规信息(n = 129)。评估采用半结构化问卷进行。在急性和社区患者中,干预组的平均总知识得分显著更高。对知识各个方面的分析表明,在副作用和预防措施方面存在明显的知识缺乏,这在干预后得到了显著改善。社区患者比住院患者更了解自己的药物治疗。所有诊断组的知识都有明显提高。年龄、性别、教育程度和药物数量均与知识提高无显著关系。总的来说,对照组有 60%的患者和传单组有 79%的患者对他们的药物信息感到满意。患者信息传单为患者和护理人员提供了一个有用的参考来源。

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