Asnet Mary J, Rubia Amal G P, Ramya G, Nagalakshmi R Nithya, Shenbagarathai R
PG & Research Department of Zoology and Biotechnology, Lady Doak College, Madurai, India.
J Vector Borne Dis. 2014 Jun;51(2):82-5.
DENVirDB is a web portal that provides the sequence information and computationally curated information of dengue viral proteins. The advent of genomic technology has increased the sequences available in the public databases. In order to create relevant concise information on Dengue Virus (DENV), the genomic sequences were collected, analysed with the bioinformatics tools and presented as DENVirDB. It provides the comprehensive information of complete genome sequences of dengue virus isolates of Southeast Asia, viz. India, Bangladesh, Sri Lanka, East Timor, Philippines, Malaysia, Papua New Guinea, Brunei and China. DENVirDB also includes the structural and non-structural protein sequences of DENV. It intends to provide the integrated information on the physicochemical properties, topology, secondary structure, domain and structural properties for each protein sequences. It contains over 99 entries in complete genome sequences and 990 entries in protein sequences, respectively. Therefore, DENVirDB could serve as a user friendly database for researchers in acquiring sequences and proteomic information in one platform.
登革病毒数据库(DENVirDB)是一个网络门户,提供登革病毒蛋白的序列信息和经计算整理的信息。基因组技术的出现增加了公共数据库中可用的序列。为了创建有关登革热病毒(DENV)的相关简明信息,收集了基因组序列,使用生物信息学工具进行分析,并呈现为DENVirDB。它提供了东南亚登革病毒分离株完整基因组序列的全面信息,即印度、孟加拉国、斯里兰卡、东帝汶、菲律宾、马来西亚、巴布亚新几内亚、文莱和中国。DENVirDB还包括登革热病毒的结构和非结构蛋白序列。它旨在为每个蛋白质序列提供有关物理化学性质、拓扑结构、二级结构、结构域和结构特性的综合信息。它分别包含99条以上的完整基因组序列条目和990条蛋白质序列条目。因此,DENVirDB可以作为一个用户友好的数据库,供研究人员在一个平台上获取序列和蛋白质组信息。