Harvill Eric T, Goodfield Laura L, Ivanov Yury, Smallridge William E, Meyer Jessica A, Cassiday Pamela K, Tondella Maria L, Brinkac Lauren, Sanka Ravi, Kim Maria, Losada Liliana
The Pennsylvania State University, University Park, Pennsylvania, USA.
Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Genome Announc. 2014 Jun 19;2(3):e00438-14. doi: 10.1128/genomeA.00438-14.
An increasing number of pertussis-like cases are attributed to the emergent pathogen Bordetella holmesii. The genomes of 9 clinical isolates show that they are clonal, lack the virulence factors encoded by B. pertussis, and are more similar to nonpertussis bordetellae. New markers for B. holmesii can be developed using these sequences.
越来越多的百日咳样病例被归因于新出现的病原体霍氏鲍特菌。9株临床分离株的基因组显示它们是克隆性的,缺乏百日咳博德特菌编码的毒力因子,并且与非百日咳鲍特菌更相似。利用这些序列可以开发霍氏鲍特菌的新标记物。