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[Bordetella holmesii bacteremia in a child with sickle cell disease].[一名镰状细胞病患儿发生霍氏博德特菌血症]
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Characterization of a highly conserved island in the otherwise divergent Bordetella holmesii and Bordetella pertussis genomes.在其他方面存在差异的霍氏博德特氏菌和百日咳博德特氏菌基因组中一个高度保守区域的特征分析
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本文引用的文献

1
Characterization of Bordetella holmesii isolates from patients with pertussis-like illness in The Netherlands.荷兰百日咳样疾病患者中霍氏博德特菌分离株的特征分析。
FEMS Immunol Med Microbiol. 2012 Mar;64(2):289-91. doi: 10.1111/j.1574-695X.2011.00911.x. Epub 2011 Dec 14.
2
Identification of a novel Acinetobacter baumannii clone in a US hospital outbreak by multilocus polymerase chain reaction/electrospray-ionization mass spectrometry.多基因聚合酶链反应/电喷雾电离质谱鉴定美国医院暴发的一种新型鲍曼不动杆菌克隆。
Diagn Microbiol Infect Dis. 2012 Jan;72(1):14-9. doi: 10.1016/j.diagmicrobio.2011.09.012. Epub 2011 Oct 19.
3
Resemblance and divergence: the "new" members of the genus Bordetella.相似与分歧：博德特氏菌属的“新”成员。
Med Microbiol Immunol. 2010 Aug;199(3):155-63. doi: 10.1007/s00430-010-0148-z.
4
Bordetella holmesii bacteremia in sickle cell disease.镰状细胞病中的霍氏博德特菌血症
Pediatr Blood Cancer. 2008 Dec;51(6):814-6. doi: 10.1002/pbc.21712.
5
The RAST Server: rapid annotations using subsystems technology.RAST服务器：使用子系统技术进行快速注释。
BMC Genomics. 2008 Feb 8;9:75. doi: 10.1186/1471-2164-9-75.
6
Identification and regulation of expression of a gene encoding a filamentous hemagglutinin-related protein in Bordetella holmesii.霍氏鲍特菌中一种丝状血凝素相关蛋白编码基因的鉴定及表达调控
BMC Microbiol. 2007 Nov 7;7:100. doi: 10.1186/1471-2180-7-100.
7
Molecular characterization of the BvgA response regulator of Bordetella holmesii.霍氏博德特氏菌BvgA反应调节因子的分子特征
Microbiol Res. 2009;164(3):243-52. doi: 10.1016/j.micres.2006.11.015. Epub 2007 Apr 2.
8
Characterization of a highly conserved island in the otherwise divergent Bordetella holmesii and Bordetella pertussis genomes.在其他方面存在差异的霍氏博德特氏菌和百日咳博德特氏菌基因组中一个高度保守区域的特征分析
J Bacteriol. 2006 Dec;188(24):8385-94. doi: 10.1128/JB.01081-06. Epub 2006 Oct 13.
9
Mutations of toluene-4-monooxygenase that alter regiospecificity of indole oxidation and lead to production of novel indigoid pigments.甲苯-4-单加氧酶的突变会改变吲哚氧化的区域特异性并导致产生新型靛类色素。
Appl Environ Microbiol. 2005 Sep;71(9):5476-83. doi: 10.1128/AEM.71.9.5476-5483.2005.
10
Functional characterization of the BvgAS two-component system of Bordetella holmesii.霍氏博德特氏菌BvgAS双组分系统的功能特性
Microbiology (Reading). 2004 Nov;150(Pt 11):3715-3729. doi: 10.1099/mic.0.27432-0.

伯克霍尔德菌属霍姆斯：新兴机会致病菌的初步基因组分析。

Bordetella holmesii: initial genomic analysis of an emerging opportunist.

机构信息

Department of Pediatrics, Columbia University, New York, NY, USA.

出版信息

Pathog Dis. 2013 Mar;67(2):132-5. doi: 10.1111/2049-632X.12028. Epub 2013 Feb 26.

DOI:10.1111/2049-632X.12028
PMID:23620158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3653170/
Abstract

Bordetella holmesii is an emerging opportunistic pathogen that causes respiratory disease in healthy individuals and invasive infections among patients lacking splenic function. We used 16S rRNA gene analysis to confirm B. holmesii as the cause of bacteremia in a child with sickle cell disease. Semiconductor-based draft genome sequencing provided insight into B. holmesii phylogeny and potential virulence mechanisms and also identified a toluene-4-monoxygenase locus unique among bordetellae.

摘要

支气管败血博德特氏菌是一种新兴的机会性病原体，可导致健康个体的呼吸道疾病和脾功能缺失患者的侵袭性感染。我们使用 16S rRNA 基因分析确认支气管败血博德特氏菌是镰状细胞病患儿菌血症的病因。基于半导体的草图基因组测序深入了解了支气管败血博德特氏菌的系统发育和潜在的毒力机制，还鉴定了博德特氏菌中独特的甲苯-4-单加氧酶基因座。