Romeo-Gabriel Mihaila, MD, PhD, "Lucian Blaga" University of Sibiu, Faculty of Medicine, Str Lucian Blaga, nr 2A, Cod 550169, Sibiu, Romania.
Pak J Med Sci. 2014 May;30(3):674-6. doi: 10.12669/pjms.303.4376.
Cardiorenal syndrome involves altering cardiac and renal function. These patients frequently develop resistance to diuretic therapy, so that ultrafiltration should be applied in emergency for saving them. Concomitant presence of an active hematologic malignancy represents an important complicating factor. We present the case of an elderly patient with acute myeloid leukemia, appeared on the background of myelodysplastic syndrome who, during marrow aplasia occurred after the first course of induction chemotherapy, developed a cardiorenal syndrome, which required repeated sessions of hemodialysis. Complete hematologic remission and efficiency of fluid depletion therapy allowed the second course of polychemotherapy, after which the patient developed an acute hepatitis C. After 8 months of complete hematologic remission that persists, the patient will be put on the standard antivirusologic treatment.
心脏肾综合征涉及心脏和肾脏功能的改变。这些患者常对利尿剂治疗产生抵抗，因此应紧急应用超滤以挽救他们。同时存在活跃的血液恶性肿瘤是一个重要的并发症。我们介绍了一位老年患者的病例，该患者患有急性髓系白血病，继发于骨髓增生异常综合征，在第一疗程诱导化疗后骨髓抑制期间发生了心脏肾综合征，需要多次血液透析。完全血液学缓解和液体耗竭治疗的效果使患者能够接受第二个多疗程化疗，此后患者发生丙型肝炎急性发作。在完全血液学缓解持续 8 个月后，患者将接受标准抗病毒治疗。
