偶然发现的脑膜瘤自发消退并伴有钙化增加。
Spontaneous regression together with increased calcification of incidental meningioma.
作者信息
Hirota Kengo, Fujita Toshiyuki, Akagawa Hiroyuki, Onda Hideaki, Kasuya Hidetoshi
机构信息
Department of Neurosurgery, Tokyo Women's Medical University Medical Center East, 2-1-10 Nishiogu, Arakawa-ku, Tokyo, 116-8567, Japan.
Tokyo Women's Medical University Institute for Integrated Medical Sciences, 8-1 Kawada-cho, Shinjyuku-ku, Tokyo, 162-8666, Japan.
出版信息
Surg Neurol Int. 2014 May 21;5:73. doi: 10.4103/2152-7806.132957. eCollection 2014.
BACKGROUND
Regression of meningioma has been reported after hemorrhage or hormonal withdrawal. However, meningioma regression is rarely observed spontaneously.
CASE DESCRIPTION
A right falx meningioma was incidentally diagnosed and was followed at every one-year by magnetic resonance imaging (MRI) for over 7 years. The tumor, with a maximum diameter of 4 cm, showed a slightly high density and was enhanced on computed tomography (CT), and a high intensity with a low-intensity core on T2 MRI, with significant edema. The meningioma gradually shrank together with a decrease of edema and increase of calcification. The initial volume, 25.5 cm(3), regressed linearly to less than half, 9.9 cm(3).
CONCLUSION
Here, we report a case of an incidentally diagnosed meningioma that regressed spontaneously. The pattern of the regression was similar to that following gamma knife radiosurgery.
背景
已有报道称脑膜瘤在出血或激素撤停后会发生消退。然而，脑膜瘤自发消退的情况很少见。
病例描述
一例右侧大脑镰脑膜瘤被偶然诊断出，随后通过磁共振成像（MRI）每年随访一次，持续了7年多。该肿瘤最大直径为4 cm，在计算机断层扫描（CT）上显示为略高密度且有强化，在T2加权MRI上呈高强度且有低强度核心，伴有明显水肿。脑膜瘤逐渐缩小，同时水肿减轻、钙化增加。初始体积为25.5 cm³，呈线性消退至不到一半，即9.9 cm³。
结论
在此，我们报告一例偶然诊断出的脑膜瘤自发消退的病例。其消退模式与伽玛刀放射外科治疗后的模式相似。
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