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日本临床实践中类风湿关节炎达标治疗策略实施的障碍

Obstacles to the implementation of the treat-to-target strategy for rheumatoid arthritis in clinical practice in Japan.

作者信息

Kaneko Yuko, Koike Takao, Oda Hiromi, Yamamoto Kazuhiko, Miyasaka Nobuyuki, Harigai Masayoshi, Yamanaka Hisashi, Ishiguro Naoki, Tanaka Yoshiya, Takeuchi Tsutomu

机构信息

Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine , Shinjuku-ku, Tokyo , Japan.

出版信息

Mod Rheumatol. 2015 Jan;25(1):43-9. doi: 10.3109/14397595.2014.926607. Epub 2014 Jun 20.

Abstract

OBJECTIVE

To clarify the obstacles preventing the implementation of the treat-to-target (T2T) strategy for rheumatoid arthritis (RA) in clinical practice.

METHODS

A total of 301 rheumatologists in Japan completed a questionnaire. In the first section, participants were indirectly questioned on the implementation of basic components of T2T, and in the second section, participants were directly questioned on their level of agreement and application.

RESULTS

Although nearly all participants set treatment targets for the majority of RA patients with moderate to high disease activity, the proportion who set clinical remission as their target was 59%, with only 45% of these using composite measures. The proportion of participants who monitored X-rays and Health Assessment Questionnaires for all their patients was 44% and 14%, respectively. The proportion of participants who did not discuss treatment strategies was 44%, with approximately half of these reasoning that this was due to a proportion of patients having a lack of understanding of the treatment strategy or inability to make decisions. When participants were directly questioned, there was a high level of agreement with the T2T recommendations.

CONCLUSION

Although there was a high level of agreement with the T2T recommendations, major obstacles preventing its full implementation still remain.

摘要

目的

阐明在临床实践中阻碍类风湿关节炎(RA)实施达标治疗(T2T)策略的障碍。

方法

日本共有301名风湿病学家完成了一份调查问卷。在第一部分,参与者被间接询问T2T基本组成部分的实施情况,在第二部分,参与者被直接询问他们的认同程度和应用情况。

结果

尽管几乎所有参与者都为大多数疾病活动度为中度至高度的RA患者设定了治疗目标,但将临床缓解作为目标的比例为59%,其中仅45%使用综合指标。对所有患者进行X线检查和健康评估问卷监测的参与者比例分别为44%和14%。未讨论治疗策略的参与者比例为44%,其中约一半的人认为这是由于一部分患者对治疗策略缺乏理解或无法做出决策。当直接询问参与者时,他们对T2T建议的认同度很高。

结论

尽管对T2T建议的认同度很高,但仍存在阻碍其全面实施的主要障碍。

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