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酷似恶性肿瘤的罕见良性病变:Whipple手术的警示故事

Rare benign pathologies mimicking malignancy: A cautionary tale for Whipple's resections.

作者信息

Ariyaratnam P, Cooke J, Dasgupta D, Wedgwood K

机构信息

Castle Hill Hospital, Cottingham, Yorkshire, UK.

出版信息

J Surg Case Rep. 2011 Feb 1;2011(2):7. doi: 10.1093/jscr/2011.2.7.

DOI:10.1093/jscr/2011.2.7
PMID:24950562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3649204/
Abstract

Benign pathologies demonstrated after a Whipple's resection (pancreatoduodenectomy) for pancreatic and peri-ampullary lesions are relatively uncommon. Here we report two cases where a Whipple's procedure was undertaken for suspected pancreaticobiliary cancer and where the final histology revealed, in each case, a rare benign lesion. The first case confirmed a cholesterol polyp in the distal common bile duct whilst the second case revealed ampullary intramural ectopic gland hyperplasia. Although pre-operative imaging helps in differentiating some benign lesions from malignant lesions, rare benign pathology may still mimic malignant conditions leading to a Whipple's resection.

摘要

在因胰腺和壶腹周围病变行胰十二指肠切除术(惠普尔手术)后发现的良性病变相对少见。在此,我们报告两例患者,他们因疑似胰胆管癌接受了惠普尔手术,但最终组织学检查在每例中均显示为罕见的良性病变。第一例确诊为胆总管远端的胆固醇息肉,而第二例显示为壶腹壁内异位腺增生。尽管术前影像学有助于区分一些良性病变和恶性病变,但罕见的良性病理仍可能酷似恶性情况,从而导致行惠普尔手术。

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本文引用的文献

1
Radical pancreaticoduodenectomy for benign disease.根治性胰十二指肠切除术治疗良性疾病。
ScientificWorldJournal. 2008 Nov 22;8:1156-67. doi: 10.1100/tsw.2008.147.
2
Ectopic pancreas presenting as ampulla of Vater tumor.表现为壶腹肿瘤的异位胰腺。
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The role of CT and endoscopic ultrasound in pre-operative staging of pancreatic cancer.CT与内镜超声在胰腺癌术前分期中的作用。
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Heterotopic pancreas mimicking cholangiocarcinoma. Case report and literature review.酷似胆管癌的异位胰腺。病例报告及文献复习。
JOP. 2007 Jan 9;8(1):28-34.
5
Ectopic pancreas in the ampulla of vater with obstructive jaundice. A case report and review of literature.伴有梗阻性黄疸的壶腹异位胰腺。病例报告及文献复习。
Dig Surg. 2006;23(4):262-4. doi: 10.1159/000096158. Epub 2006 Oct 10.
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Surgery for pancreatic cancer: recent controversies and current practice.胰腺癌手术:近期争议与当前实践
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7
Preoperative staging and tumor resectability assessment of pancreatic cancer: prospective study comparing endoscopic ultrasonography, helical computed tomography, magnetic resonance imaging, and angiography.胰腺癌的术前分期及肿瘤可切除性评估:比较内镜超声、螺旋计算机断层扫描、磁共振成像及血管造影的前瞻性研究
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8
Gallbladder polyps, cholesterolosis, adenomyomatosis, and acute acalculous cholecystitis.胆囊息肉、胆固醇沉着症、腺肌增生症和急性非结石性胆囊炎。
Semin Gastrointest Dis. 2003 Oct;14(4):178-88.
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Gallbladder polyps: epidemiology, natural history and management.胆囊息肉:流行病学、自然史及管理
Can J Gastroenterol. 2002 Mar;16(3):187-94. doi: 10.1155/2002/787598.
10
Obstructive jaundice caused by a cholesterol polyp of the gallbladder: report of a case.胆囊胆固醇息肉引起的梗阻性黄疸:一例报告
Surg Today. 1994;24(12):1104-6. doi: 10.1007/BF01367466.