将赛沛Xpert® SA鼻拭子全基因PCR检测法与培养法进行比较，以检测甲氧西林敏感和耐甲氧西林金黄色葡萄球菌定植情况。
Performance of the Cepheid Xpert® SA Nasal Complete PCR assay compared to culture for detection of methicillin-sensitive and methicillin-resistant Staphylococcus aureus colonization.
作者信息
Patel Parul A, Schora Donna M, Peterson Kari E, Grayes Althea, Boehm Susan, Peterson Lance R
机构信息
NorthShore University Health System, Evanston, IL.
NorthShore University Health System, Evanston, IL.
出版信息
Diagn Microbiol Infect Dis. 2014 Sep;80(1):32-4. doi: 10.1016/j.diagmicrobio.2014.05.019. Epub 2014 May 21.
Sensitivity, specificity, positive predictive value, and negative predictive value for the Cepheid Xpert® SA Nasal Complete detection (N = 971) of methicillin-sensitive Staphylococcus aureus was 86.5%, 98.5%, 94.6%, and 96.1%; detection of methicillin-resistant S. aureus was 89.3%, 97.9%, 79.8%, and 99.0%, respectively. Our results show that testing on long-term care facility patients had lower sensitivity and specificity compared to acute care patient results.
针对耐甲氧西林金黄色葡萄球菌，赛沛Xpert® SA鼻腔全检法（样本量N = 971）的灵敏度、特异度、阳性预测值和阴性预测值分别为86.5%、98.5%、94.6%和96.1%；针对耐甲氧西林金黄色葡萄球菌的检测结果分别为89.3%、97.9%、79.8%和99.0%。我们的结果表明，与急性护理患者的检测结果相比，对长期护理机构患者进行检测的灵敏度和特异度较低。
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