The Danish Medical Device Industry Association, Gl. Strandvej 16, DK-2990 Nivå, Denmark.
Research Centre on Biotech Business, Copenhagen Business School, Kilevej 14A, DK-2000 Frederiksberg, Denmark.
Drug Discov Today. 2014 Nov;19(11):1699-1710. doi: 10.1016/j.drudis.2014.06.011. Epub 2014 Jun 19.
Academic drug discovery centres (ADDCs) are seen as one of the solutions to fill the innovation gap in early drug discovery, which has proven challenging for previous organisational models. Prior studies of ADDCs have identified the need to analyse them from the angle of their economic and organisational sustainability. We take that angle in an in-depth study of four prominent ADDCs. Our findings indicate that there are clear similarities in the way sustainable centres are organised, managed and financed. We also identify factors in the frameworks of academia and research funding affecting their performance.
学术药物研发中心(ADDC)被视为解决早期药物研发创新缺口的方案之一,此前的组织模式在这方面一直面临挑战。先前对 ADDC 的研究已经确定需要从经济和组织可持续性的角度对它们进行分析。我们从四个知名 ADDC 的深入研究中采用了这个角度。我们的研究结果表明,可持续中心在组织、管理和融资方面具有明显的相似之处。我们还确定了影响其绩效的学术和研究资金框架中的因素。