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保险状况和父母教育程度对1型糖尿病青少年血糖控制及心血管疾病风险状况的影响。

The effect of insurance status and parental education on glycemic control and cardiovascular disease risk profile in youth with Type 1 Diabetes.

作者信息

Majidi Shideh, Wadwa R Paul, Bishop Franziska K, Klingensmith Georgeanna J, Rewers Marian, McFann Kim, Maahs David M

机构信息

Department of Pediatrics, Children's Hospital Colorado, 13123 E. 16th Ave, Aurora, CO 80045, USA ; Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, 1775 Aurora Ct, Aurora, CO 80045, USA.

Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, 1775 Aurora Ct, Aurora, CO 80045, USA.

出版信息

J Diabetes Metab Disord. 2014 May 22;13:59. doi: 10.1186/2251-6581-13-59. eCollection 2014.

Abstract

BACKGROUND

Adult studies have shown a correlation between low socioeconomic status and Type 1 Diabetes complications, but studies have not been done in children to examine the effect of socioeconomic status on risk for future complications. This study investigates the relationship between insurance status and parental education and both glycemic control and cardiovascular disease (CVD) risk factors in youth with type 1 diabetes.

METHODS

A cross-sectional study of 295 youth with established type 1 diabetes who underwent examination with fasting blood draw and reported insurance status and parental education.

RESULTS

Youth with type 1 diabetes and public insurance had higher hemoglobin A1c (HbA1c), body mass index, hs-CRP, and blood pressure (p < 0.05) than those with private insurance. Insulin regimen varied between insurance groups, and differences in HbA1c and CVD risk factors, except for diastolic blood pressure (DBP), were no longer evident after controlling for insulin regimen. Parental education was not associated with HbA1c or CVD risk factors.

CONCLUSIONS

Youth with type 1 diabetes and public insurance have worse glycemic control and elevated CVD risk factors compared to those with private insurance, but this was no longer seen when insulin regimen was controlled for. Further research is needed to look at differences between those with public insurance and private insurance that contribute to differences in type 1 diabetes outcomes, and to identify modifiable risk factors in pediatric patients in order to focus earlier interventions to decrease and prevent future diabetes complications.

摘要

背景

成人研究表明社会经济地位低下与1型糖尿病并发症之间存在关联,但尚未针对儿童开展研究以考察社会经济地位对未来并发症风险的影响。本研究调查了1型糖尿病青少年的保险状况和父母教育程度与血糖控制及心血管疾病(CVD)风险因素之间的关系。

方法

对295名已确诊1型糖尿病的青少年进行横断面研究,这些青少年接受了空腹抽血检查,并报告了保险状况和父母教育程度。

结果

患有1型糖尿病且参加公共保险的青少年,其糖化血红蛋白(HbA1c)、体重指数、超敏C反应蛋白(hs-CRP)和血压均高于参加私人保险的青少年(p < 0.05)。不同保险组的胰岛素治疗方案有所不同,在控制胰岛素治疗方案后,除舒张压(DBP)外,HbA1c和CVD风险因素的差异不再明显。父母教育程度与HbA1c或CVD风险因素无关。

结论

与参加私人保险的1型糖尿病青少年相比,参加公共保险的青少年血糖控制较差且CVD风险因素升高,但在控制胰岛素治疗方案后这种差异不再明显。需要进一步研究以探讨参加公共保险和私人保险的青少年之间导致1型糖尿病结局差异的因素,并确定儿科患者中可改变的风险因素,以便更早地进行干预以减少和预防未来的糖尿病并发症。

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