科威特肺结核治疗中断的决定因素。
Determinants of default from pulmonary tuberculosis treatment in Kuwait.
作者信息
Zhang Qing, Gaafer Mohamed, El Bayoumy Ibrahim
机构信息
Tuberculosis Diagnosis and Treatment Center, Shanghai, Pulmonary Hospital, School of Medicine, Tongji University, 507 Zheng Min Road, Shanghai 200433, China.
Community, Environmental and Occupational Medicine Department, Minufiya University, Egypt.
出版信息
ScientificWorldJournal. 2014;2014:672825. doi: 10.1155/2014/672825. Epub 2014 Apr 6.
OBJECTIVES
To determine the prevalence and risk factors of default from pulmonary tuberculosis treatment in Kuwait.
DESIGN
Retrospective study.
PATIENTS AND METHODS
We studied all patients who were registered for pulmonary tuberculosis treatment between January 1, 2010, and December 31, 2012, and admitted into TB wards in El Rashid Center or treated in the outpatient clinic in TB Control Unit.
RESULTS
There were 110 (11.5%) patients who defaulted from treatment. Fifty-six percent of those who defaulted did so in the first 2 months of treatment and 86.4% of them were still bacteriologically positive at the time of default. Key risk factors associated with noncompliance were male sex, low educational level, non-Kuwaiti nations, history of default, and history of concomitant diabetes mellitus, liver disease, or lung cancer. Multiple drug resistance was also associated with default from treatment.
CONCLUSION
Default from treatment may be partially responsible for the persistent relatively high rates of tuberculosis in Kuwait. Health professionals and policy makers should ensure that all barriers to treatment are removed and that incentives are used to encourage treatment compliance.
目的
确定科威特肺结核治疗中断的患病率及危险因素。
设计
回顾性研究。
患者与方法
我们研究了2010年1月1日至2012年12月31日期间登记接受肺结核治疗并入住拉希德中心结核病病房或在结核病控制单位门诊接受治疗的所有患者。
结果
有110名（11.5%）患者治疗中断。治疗中断的患者中，56%在治疗的前2个月内中断治疗，其中86.4%在中断治疗时仍为细菌学阳性。与不依从相关的关键危险因素包括男性、低教育水平、非科威特国籍、治疗中断史以及合并糖尿病、肝病或肺癌史。多重耐药也与治疗中断有关。
结论
治疗中断可能是科威特结核病持续相对高发的部分原因。卫生专业人员和政策制定者应确保消除所有治疗障碍，并采用激励措施鼓励患者坚持治疗。
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