Postgraduate Institute of Medicine, University of Colombo, Sri Lanka.
Regional Director of Health Services, Kalutara District, Sri Lanka.
Indian J Tuberc. 2021 Apr;68(2):266-271. doi: 10.1016/j.ijtb.2020.09.018. Epub 2020 Sep 28.
Tuberculosis (TB) is an ancient disease and remains to be a public health problem all over the world. Noncompliance of treatment among TB patients affect the control of disease, leading to increased burden of the disease, mortality, drug resistant and relapse. Assessing the factors associated with noncompliance of TB treatment will be useful to reduce the noncompliance and burden.
To assess the factors associated with noncompliance of treatment among TB patients in intensive phase at Kalutara District, Sri Lanka.
A descriptive cross-sectional study was conducted among the new TB patients registered at District Chest Clinic (DCC), Kalutara for a period of six months. A questionnaire was administered for total study population registered during the data collection period. The relevant data were abstracted from registers and records maintaining at the DCC.
Data were collected from 252 patients [males = 160 (63.5%) and females = 92 (36.5%)]. The percentage of noncompliance was 18.3% (n = 46) among newly diagnosed TB patients. Only 13.5% (n = 34) of TB patients visited Directly Observed Treatment, short-course (DOTS) provider daily. Majority (61.9%, n = 156) of DOTS providers did not observe for drug intake. The factors significantly associated with noncompliance for TB treatment were (1) not observing the drug intake by DOTS providers, (2) side effects of the drugs, (3) educational level, (4) living environment and (5) absent of a care giver.
Noncompliance of treatment is still a common problem among TB patients. Special emphasis should be made on TB patients based on the factors associated with the noncompliance of the treatment. DOTS providers should adhere to DOTS policy.
结核病（TB）是一种古老的疾病，仍然是全世界的公共卫生问题。结核病患者不遵守治疗方案会影响疾病的控制，导致疾病负担增加、死亡率上升、耐药和复发。评估与结核病患者治疗不依从相关的因素将有助于减少不依从和负担。
评估斯里兰卡卡卢特勒区强化期结核病患者治疗不依从的相关因素。
在卡卢特勒区胸科诊所（DCC）对新登记的结核病患者进行了为期六个月的描述性横断面研究。在数据收集期间，对登记的所有研究人群进行了问卷调查。从 DCC 保存的登记册和记录中提取相关数据。
共收集了 252 名患者[男性 160 名（63.5%），女性 92 名（36.5%）]。新诊断结核病患者中不依从的比例为 18.3%（n=46）。仅有 13.5%（n=34）的结核病患者每天到直接观察治疗短期疗程（DOTS）提供者处就诊。大多数（61.9%，n=156）DOTS 提供者未观察药物摄入情况。与结核病治疗不依从显著相关的因素包括：（1）DOTS 提供者未观察药物摄入情况；（2）药物副作用；（3）教育水平；（4）居住环境；（5）无照顾者。
治疗不依从仍然是结核病患者中常见的问题。应根据与治疗不依从相关的因素，特别关注结核病患者。DOTS 提供者应遵守 DOTS 政策。
