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经口机器人手术切除的功能结局、可行性及安全性:单机构连续35例口咽鳞状细胞癌经口机器人手术系列研究

Functional outcomes, feasibility, and safety of resection of transoral robotic surgery: single-institution series of 35 consecutive cases of transoral robotic surgery for oropharyngeal squamous cell carcinoma.

作者信息

Lörincz Balazs B, Möckelmann Nikolaus, Busch Chia-Jung, Knecht Rainald

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery and Oncology, Head and Neck Cancer Centre of the Hubertus Wald University Cancer Centre Hamburg, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Head Neck. 2015 Nov;37(11):1618-24. doi: 10.1002/hed.23809. Epub 2014 Aug 28.

Abstract

BACKGROUND

This is a single-institution prospective study in a tertiary care center to evaluate feasibility, completeness of resection, and functional outcomes for oropharyngeal squamous cell carcinoma (SCC) treated primarily with transoral robotic-assisted resection.

METHODS

Thirty-five patients with T1 and T2 squamous cell carcinoma of the oropharynx were included. They underwent transoral robotic surgery (TORS) between September 2011 and April 2013, with a median follow-up time of 13 months.

RESULTS

Main outcome measures were completeness of resection, disease-free survival, and cancer recurrence for the preliminary oncologic outcome; postoperative bleeding, number of days intubated, rate of elective tracheotomy, duration of intensive care and/or intermediate care, speech and swallowing function, and length of nasogastric and/or gastrostomy tube dependency for the functional results.

CONCLUSION

Our 1-year (median) functional and early oncologic results of 35 patients with oropharyngeal cancer treated primarily with TORS are encouraging to continue gaining further experiences with this surgical modality on a select subgroup of patients.

摘要

背景

这是一项在三级医疗中心进行的单机构前瞻性研究,旨在评估主要采用经口机器人辅助切除术治疗的口咽鳞状细胞癌(SCC)的可行性、切除完整性和功能结局。

方法

纳入35例口咽T1和T2期鳞状细胞癌患者。他们在2011年9月至2013年4月期间接受了经口机器人手术(TORS),中位随访时间为13个月。

结果

主要结局指标包括初步肿瘤学结局的切除完整性、无病生存率和癌症复发率;功能结果的术后出血、插管天数、选择性气管切开率、重症监护和/或中级护理持续时间、言语和吞咽功能以及鼻胃管和/或胃造瘘管依赖时间。

结论

我们对35例主要采用TORS治疗的口咽癌患者进行的1年(中位)功能和早期肿瘤学结果令人鼓舞,促使我们继续在特定亚组患者中积累这种手术方式的更多经验。

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