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腹腔镜单孔(LESS)机器人辅助部分肾切除术(RAPN)可减轻术后伤口疼痛,且并发症发生率不会增加。

Laparoendoscopic single-site (LESS) robot-assisted partial nephrectomy (RAPN) reduces postoperative wound pain without a rise in complication rates.

作者信息

Shin Tae Young, Lim Sey Kiat, Komninos Christos, Kim Dong Wook, Han Woong Kyu, Hong Sung Jun, Jung Byung Ha, Rha Koon Ho

机构信息

Department of Urology, Chuncheon Sacred Hospital, Hallym University College of Medecine, Chuncheon, Korea.

出版信息

BJU Int. 2014 Oct;114(4):555-61. doi: 10.1111/bju.12783. Epub 2014 Aug 11.

Abstract

OBJECTIVE

To compare long-term functional outcomes and pain scale scores of patients who underwent laparoendoscopic single-site (LESS)- robot-assisted partial nephrectomy (RAPN) to those who underwent conventional RAPN (C-RAPN), as LESS surgery is increasingly being adopted by urologists worldwide to reduce morbidities and scarring associated with surgical interventions.

PATIENTS AND METHODS

In all, 167 consecutive patients who had RAPN were identified from our Institutional Review Board-approved computerised database between October 2006 to July 2012. Patients were stratified into two groups: 80 patients who underwent C-RAPN and 79 who underwent LESS-RAPN.

RESULTS

The LESS-RAPN group had a longer warm ischaemia time [WIT, mean (sd) 26.5 (10.5) vs 19.8 (13.1) min; P = 0.001] and total operation time [TOT, mean (sd) 210.3 (83.4) vs 183.1 (76.1) min; P = 0.033] when compared with the C-RAPN group. While, the LESS-RAPN group and C-RAPN group were not significantly different for the number of patients with negative surgical margins [77 (96.2%) vs 73 (91.4%); P = 0.194), absolute change in postoperative renal function [mean (sd) -6.5 (16.7)% vs -7.6 (16.7)%; P = 0.738) and postoperative complications rate [12 (15.0%) vs 10 (12.6%); P = 0.279). Furthermore, the LESS-RAPN group had lower visual analogue pain scale (VAPS) scores at discharge [mean (sd) 2.1 (1.3) vs 1.7 (1.0); P = 0.048].

CONCLUSIONS

Despite a significantly longer WIT and TOT, the functional outcomes of LESS-RAPN were comparable to those of C-RAPN for tumours of similar mean sizes and complexities, without any detriments in oncological and complications outcomes. On discharge, patients who underwent LESS-RAPN also reported lower pain levels as one of the advantages of minimally invasive surgery. With the development of instrumentation specifically designed for single-site surgery, LESS could be more easily conducted in patients who are interested in improved quality of life outcomes.

摘要

目的

比较接受腹腔镜单孔(LESS)机器人辅助部分肾切除术(RAPN)的患者与接受传统RAPN(C-RAPN)的患者的长期功能结局和疼痛量表评分,因为全球泌尿外科医生越来越多地采用LESS手术来减少与手术干预相关的发病率和瘢痕形成。

患者与方法

从2006年10月至2012年7月我们机构审查委员会批准的计算机数据库中,共识别出167例连续接受RAPN的患者。患者被分为两组:80例接受C-RAPN的患者和79例接受LESS-RAPN的患者。

结果

与C-RAPN组相比,LESS-RAPN组的热缺血时间更长[WIT,平均值(标准差)26.5(10.5)分钟 vs 19.8(13.1)分钟;P = 0.001]和总手术时间更长[TOT,平均值(标准差)210.3(83.4)分钟 vs 183.1(76.1)分钟;P = 0.033]。然而,LESS-RAPN组和C-RAPN组在手术切缘阴性患者数量[77例(96.2%) vs 73例(91.4%);P = 0.194]、术后肾功能的绝对变化[平均值(标准差)-6.5(16.7)% vs -7.6(16.7)%;P = 0.738]和术后并发症发生率[12例(15.0%) vs 10例(12.6%);P = 0.279]方面无显著差异。此外,LESS-RAPN组出院时视觉模拟疼痛量表(VAPS)评分更低[平均值(标准差)2.1(1.3) vs 1.7(1.0);P = 0.048]。

结论

尽管LESS-RAPN的WIT和TOT明显更长,但对于平均大小和复杂性相似的肿瘤,LESS-RAPN的功能结局与C-RAPN相当,在肿瘤学和并发症结局方面没有任何损害。出院时,接受LESS-RAPN的患者也报告疼痛程度更低,这是微创手术的优势之一。随着专门为单孔手术设计的器械的发展,LESS可能更容易在对改善生活质量结局感兴趣的患者中进行。

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