Radomiljac Jordan D, Whelan James, van der Merwe Margaretha
Australian Research Council Centre of Excellence in Plant Energy Biology, 4th Floor Bayliss Building M316, University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia.
Metabolites. 2013 Sep 6;3(3):761-86. doi: 10.3390/metabo3030761.
Metabolic configuration and adaptation under a range of abiotic stresses, including drought, heat, salinity, cold, and nutrient deprivation, are subjected to an intricate span of molecular pathways that work in parallel in order to enhance plant fitness and increase stress tolerance. In recent years, unprecedented advances have been made in identifying and linking different abiotic stresses, and the current challenge in plant molecular biology is deciphering how the signaling responses are integrated and transduced throughout metabolism. Metabolomics have often played a fundamental role in elucidating the distinct and overlapping biochemical changes that occur in plants. However, a far greater understanding and appreciation of the complexity in plant metabolism under specific stress conditions have become apparent when combining metabolomics with other-omic platforms. This review focuses on recent advances made in understanding the global changes occurring in plant metabolism under abiotic stress conditions using metabolite profiling as an integrated discovery platform.
在一系列非生物胁迫（包括干旱、高温、盐度、低温和养分缺乏）下，植物的代谢构型和适应性受到一系列复杂分子途径的调控，这些途径并行发挥作用，以增强植物的适应性并提高胁迫耐受性。近年来，在识别和关联不同非生物胁迫方面取得了前所未有的进展，而植物分子生物学当前面临的挑战是解读信号反应如何在整个代谢过程中整合和传导。代谢组学在阐明植物中发生的独特和重叠生化变化方面常常发挥着重要作用。然而，当将代谢组学与其他组学平台相结合时，人们对特定胁迫条件下植物代谢复杂性的理解和认识有了更显著的提升。本综述重点介绍了利用代谢物谱分析作为综合发现平台，在理解非生物胁迫条件下植物代谢发生的全局变化方面取得的最新进展。
