Kanatani Kumiko T, Adachi Yuichi, Sugimoto Nobuo, Noma Hisashi, Onishi Kazunari, Hamazaki Kei, Takahashi Yoshimitsu, Ito Isao, Egawa Miho, Sato Keiko, Go Tohshin, Kurozawa Youichi, Inadera Hidekuni, Konishi Ikuo, Nakayama Takeo
Department of Health Informatics, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Department of Paediatrics, Faculty of Medicine, University of Toyama, Toyama, Japan.
BMJ Open. 2014 Jun 23;4(6):e004863. doi: 10.1136/bmjopen-2014-004863.
Desert dust is estimated to constitute about 35% of aerosol in the troposphere. Desertification, climatic variability and global warming all can contribute to increased dust formation. This study aims to examine possible health effects of desert dust exposure on pregnant women and their children. The purpose of this report was to present the study protocol.
This 4-year birth cohort study began in 2011 as an adjunct study of the Japan Environment & Children's Study (JECS) involving three regions: Kyoto, Toyama and Tottori. The JECS participants of the three regions above who also agreed to participate in this adjunct study were enrolled prior to delivery. Light Detecting and Ranging (LIDAR) with a polarisation analyser, which can distinguish mineral dust particles from other particles, is used for exposure measurements. Outcomes are allergic symptoms for mothers and development of asthma and other allergic or respiratory diseases for their children. Data are acquired in a timely manner by connecting local LIDAR equipment to an online questionnaire system. Participants answer the online questionnaire using mobile phones or personal computers.
The study protocol was approved by the ethics committees of Kyoto University, University of Toyama and Tottori University. All participants provided written informed consent. The results of this study will be published in peer-reviewed journals and disseminated to the scientific community and general public.
UMIN000010826.
据估计，沙漠尘埃约占对流层气溶胶的35%。荒漠化、气候多变性和全球变暖都可能导致沙尘形成增加。本研究旨在探讨接触沙漠尘埃对孕妇及其子女可能产生的健康影响。本报告的目的是介绍研究方案。
这项为期4年的出生队列研究始于2011年，作为日本环境与儿童研究（JECS）的一项附属研究，涉及京都、富山和鸟取三个地区。上述三个地区同意参与这项附属研究的JECS参与者在分娩前被纳入研究。使用带有偏振分析仪的光探测与测距（LIDAR）技术，该技术可以区分矿物尘埃颗粒与其他颗粒，用于暴露测量。观察指标为母亲的过敏症状以及其子女哮喘和其他过敏性或呼吸道疾病的发生情况。通过将当地的LIDAR设备连接到在线问卷系统，及时获取数据。参与者使用手机或个人电脑回答在线问卷。
研究方案已获得京都大学、富山大学和鸟取大学伦理委员会的批准。所有参与者均提供了书面知情同意书。本研究结果将发表在同行评审期刊上，并向科学界和公众传播。
UMIN000010826。
