Willemse P H, de Jong P E, Elema J D, Mulder N H
Department of Internal Medicine, University Hospital Groningen, The Netherlands.
Cancer Chemother Pharmacol. 1989;23(5):329-30. doi: 10.1007/BF00292414.
A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion. Biopsy findings, the possible underlying mechanism, and the existing literature are discussed.
一名62岁女性在反复使用异环磷酰胺（IFX）后出现亚急性肾衰竭，尽管同时持续输注2-巯基乙烷磺酸钠（美司钠）。本文讨论了活检结果、可能的潜在机制及现有文献。
