Lee Audrey, Varma Arjun, Boro Maureen, Korman Nancy
Professor of Pharmacy Practice and Regional Coordinator, University of the Pacific (UOP), Thomas J. Long (TJL) School of Pharmacy and Health Sciences; Clinical Associate Professor, University of California at San Francisco (UCSF), School of Pharmacy; and Clinical Pharmacist, Internal Medicine , San Francisco VA Medical Center (SFVAMC) .
Ambulatory Care Pharmacist, Kaiser Permanente Richmond , California .
Hosp Pharm. 2014 Jun;49(6):530-8. doi: 10.1310/hpj4906-530.
Few studies have explored the impact of using different methods for obtaining accurate medication histories on medication safety. This study was conducted to compare the accuracy and clinical impact of pharmacist medication histories obtained by electronic medical record review (EMRR) alone with those obtained by direct interviews combined with EMRR.
This 18-week prospective study included patients who were admitted to the Inpatient Medicine Service at the study institution and who had a pharmacist-conducted medication reconciliation EMRR within 48 hours of hospital admission. A chart review was performed to collect data to determine whether differences existed in the number of discrepancies, recommendations, and medication errors between the EMRR alone group compared to the EMRR combined with the patient interview group.
Five hundred thirteen discrepancies were identified with the EMRR group compared to 986 from the combined EMRR and patient interview group (P < .001). Significantly more recommendations were made in the combination interview group compared to the EMRR alone group (260 vs 97; P < .001). Fewer medication errors were identified for the EMRR alone group compared to the combination interview group (55 vs 134; P < .001). The most common errors were omitted medications followed by extra dose/failure to discontinue therapy and wrong dose/frequency errors.
Pharmacist-conducted admission medication interviews combined with EMRR can potentially identify harmful medication discrepancies and prevent medication errors.
很少有研究探讨采用不同方法获取准确用药史对用药安全的影响。本研究旨在比较仅通过电子病历回顾(EMRR)获取的药师用药史与通过直接访谈结合EMRR获取的药师用药史的准确性及临床影响。
这项为期18周的前瞻性研究纳入了入住研究机构内科病房的患者,这些患者在入院48小时内接受了药师进行的用药核对EMRR。进行病历审查以收集数据,确定仅EMRR组与EMRR结合患者访谈组之间在差异数量、建议数量和用药错误方面是否存在差异。
EMRR组识别出513处差异,而EMRR与患者访谈相结合的组识别出986处差异(P <.001)。与仅EMRR组相比,联合访谈组提出的建议明显更多(260条对97条;P <.001)。与联合访谈组相比,仅EMRR组识别出的用药错误更少(55处对134处;P <.001)。最常见的错误是漏服药物,其次是额外剂量/未停药和错误剂量/频率错误。
药师进行的入院用药访谈结合EMRR有可能识别有害的用药差异并预防用药错误。