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急性髓系白血病的临床血液学研究

Clinico-hematological study of acutemyeloid leukemias.

作者信息

C R Preethi

机构信息

Assistant Professor, Department of Pathology, JJM Medical College , Davangere, India .

出版信息

J Clin Diagn Res. 2014 Apr;8(4):FC14-7. doi: 10.7860/JCDR/2014/7854.4298. Epub 2014 Apr 15.

Abstract

CONTEXT

Acute Myeloid leukemia has been of special interest to innumerable workers in the field of cancer research since the blood and haematopoietic tissue can be easily and repeatedly sampled.

AIM

To know the relative incidence of Acute myeloid leukemia among the patients referred for complete haemogram at the Department of Pathology, JJMMC, Davangere, India.To study the clinical manifestations and their correlation with various types of acute myeloid leukemia.To study the haematological profiles in acute myeloid leukemia.

SETTINGS AND DESIGN

This was a hospital based study conducted at haematology unit, Department of Pathology, JJM Medical College, Davangere, India.

MATERIALS AND METHOD

The present study was done during the period of June 2006 to May 2008 at haematology unit department of Pathology, JJM Medical College, Davangere, India. Cases from Chigateri General Hospital, Bapuji Hospital and other private hospitals situated in and around Davangere were included for the study. The case selection was based on the clinical features and supported by laboratory evidence. Bone marrow aspiration was subsequently carried out after obtaining written consent from the patient or the guardian.

STATISTICS

The results were expressed in percentage.

RESULTS AND CONCLUSION

A total of 1039 patients who were referred to the Department of Haematology out of which 50 patients were diagnosed as Acute Myeloid Leukemia. The present study highlighted that light microscopic features of peripheral smear and bone marrow will still remain mainstay in the diagnosis of acute leukemias.

摘要

背景

急性髓系白血病一直是癌症研究领域无数工作者特别关注的对象,因为血液和造血组织可以轻松且反复地进行采样。

目的

了解在印度达万盖尔市JJMMC病理科进行全血细胞计数检查的患者中急性髓系白血病的相对发病率。研究急性髓系白血病的临床表现及其与各种类型急性髓系白血病的相关性。研究急性髓系白血病的血液学特征。

设置与设计

这是一项在印度达万盖尔市JJM医学院病理科血液学单元进行的基于医院的研究。

材料与方法

本研究于2006年6月至2008年5月在印度达万盖尔市JJM医学院病理科血液学单元进行。纳入了来自奇加泰里综合医院、巴普吉医院以及达万盖尔市及其周边的其他私立医院的病例进行研究。病例选择基于临床特征并得到实验室证据的支持。在获得患者或监护人的书面同意后,随后进行骨髓穿刺。

统计学方法

结果以百分比表示。

结果与结论

共有1039名患者被转诊至血液科,其中50名患者被诊断为急性髓系白血病。本研究强调外周血涂片和骨髓的光镜特征仍然是急性白血病诊断的主要依据。

相似文献

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Clinico-hematological study of acutemyeloid leukemias.急性髓系白血病的临床血液学研究
J Clin Diagn Res. 2014 Apr;8(4):FC14-7. doi: 10.7860/JCDR/2014/7854.4298. Epub 2014 Apr 15.
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Pancytopenia: a clinico hematological study.全血细胞减少症:一项临床血液学研究。
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