Giuliano Vincenzo, Giuliano Concetta
Breast Cancer Research Institute, Nova Southeastern University College of Osteopathic Medicine, 5732 Canton Cove, Winter Springs, FL 32708, USA.
ISRN Radiol. 2012 Oct 23;2013:235270. doi: 10.5402/2013/235270. eCollection 2013.
This investigation is part of an ongoing large scale study using volumetric breast ultrasound (VBUS) as a screening modality in mammographically dense breasts, offering a substantial benefit to MR imaging of the breast in terms of cost and efficiency. The addition of VBUS to mammography in women with greater than 50% breast density resulted in the detection of 12.3 per 1,000 breast cancers, compared to 4.6 per 1,000 by mammography alone with an overall attributable risk of breast cancer of 19.92 (95% confidence level, 16.75-23.61) in our screened population. These preliminary results may justify the cost benefit of implementing the judicious use of VBUS as an alternative to MR imaging of the breast in conjunction with mammography in the dense breast screening population.
本研究是一项正在进行的大规模研究的一部分，该研究使用容积乳腺超声（VBUS）作为乳腺钼靶致密型乳房的筛查方式，在成本和效率方面为乳腺磁共振成像带来了显著益处。在乳腺密度大于50%的女性中，将VBUS添加到乳腺钼靶检查中，每1000例乳腺癌的检测率为12.3例，而仅用乳腺钼靶检查时每1000例为4.6例，在我们的筛查人群中，乳腺癌的总体归因风险为19.92（95%置信水平，16.75 - 23.61）。这些初步结果可能证明，在致密型乳房筛查人群中，明智地使用VBUS作为乳腺磁共振成像结合乳腺钼靶检查的替代方法具有成本效益。
