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罗萨伊-多夫曼病表现为单侧慢性腮腺炎。

Rosai Dorfman Disease presenting as unilateral chronic parotitis.

作者信息

Byrd Jk, Overton Lj, Goldin Ta, Lentsch Ej

机构信息

Medical University of South Carolina, Charleston, USA.

出版信息

J Surg Case Rep. 2012 Jun 1;2012(6):7. doi: 10.1093/jscr/2012.6.7.

DOI:10.1093/jscr/2012.6.7
PMID:24960676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3862464/
Abstract

We report a 48-year-old man who presents with a 20-month history of left parotid enlargement despite treatment with antibiotics and steroids. He presented with a non-painful palpable mass in his left parotid without facial weakness or otologic symptoms. Fine needle aspiration was inconclusive, and an attempted excisional biopsy was aborted due to involvement of the facial nerve and suspicion of lymphoma. Subsequently, he underwent a total parotidectomy with facial nerve preservation. The specimen yielded results that were consistent with Rosai-Dorfman disease. Of note in our patient is the lack of cervical lymphadenopathy, which classically presents with this condition. Head and neck extranodal involvement, while not unusual for Rosai-Dorfman, is rarely seen in the parotid. Previous reports of this disease found in the parotid indicate an underlying autoimmune process, which was not found in this patient.

摘要

我们报告了一名48岁男性,尽管接受了抗生素和类固醇治疗,但仍有20个月的左腮腺肿大病史。他左侧腮腺出现一个无痛性可触及肿块,无面部无力或耳部症状。细针穿刺活检结果不明确,由于面神经受累及怀疑淋巴瘤,尝试的切除活检中止。随后,他接受了保留面神经的全腮腺切除术。标本结果与罗萨伊-多夫曼病一致。值得注意的是,我们的患者没有颈淋巴结病,而这种疾病通常会出现颈淋巴结病。头颈部结外受累在罗萨伊-多夫曼病中并不罕见,但在腮腺中很少见。先前在腮腺中发现这种疾病的报告表明存在潜在的自身免疫过程,而该患者未发现此情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/7bfe771f0af7/jscr-2012-6-7fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/999cba132ff6/jscr-2012-6-7fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/7a0580707e6a/jscr-2012-6-7fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/3ffd5db59307/jscr-2012-6-7fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/7bfe771f0af7/jscr-2012-6-7fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/999cba132ff6/jscr-2012-6-7fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/7a0580707e6a/jscr-2012-6-7fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/3ffd5db59307/jscr-2012-6-7fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fb/3862464/7bfe771f0af7/jscr-2012-6-7fig4.jpg

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1
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本文引用的文献

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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): imaging manifestations in the head and neck.伴巨大淋巴结病的窦性组织细胞增生症(罗萨伊 - 多夫曼病):头颈部的影像学表现
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Rosai-Dorfman disease presenting as a parotid mass.
以腮腺肿块为表现的罗萨伊-多夫曼病。
J Laryngol Otol. 1997 Nov;111(11):1091-3. doi: 10.1017/s0022215100139441.
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Immunologic abnormalities and their significance in sinus histiocytosis with massive lymphadenopathy.免疫异常及其在伴巨大淋巴结病的窦性组织细胞增多症中的意义。
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Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity.伴有巨大淋巴结病的窦性组织细胞增多症。一种新认识的良性临床病理实体。
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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity.伴有巨大淋巴结病的窦组织细胞增生症(罗萨伊-多夫曼病):该实体的综述
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Sinus histiocytosis with massive lymphadenopathy.伴巨大淋巴结病的窦性组织细胞增生症
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